prikaz prve stranice dokumenta Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction
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Scientific paper - Review paper
Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction
Critical reviews in clinical laboratory sciences, 53 (2016), 6; 379-395. https://doi.org/10.1080/10408363.2016.1190682
Foster, Brandon; Balassa, Timea; Benen, Thomas; Dominović, Marin; Elmadjian, Gabriel; Florova, Violetta; Fransolet, Maite; Kestlerova, Andrea; Kmiecik, Gabriela; Kostadinova, Irena; Kyvelidou, Christiana; Meggyes, Matyas; Mincheva, Mina; Moro, Laura; Pastuschek, Jana; Spoldi, Valentina; Wandernoth, Petra; Weber, Maja; Toth, Bettina; Markert, Udo More authors...

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Cite this document

Foster, B., Balassa, T., Benen, T., Dominović, M., Elmadjian, G., Florova, V. ... Markert, U. (2016). Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction. Critical reviews in clinical laboratory sciences, 53. (6), 379-395. doi: 10.1080/10408363.2016.1190682

Foster, Brandon, et al. "Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction." Critical reviews in clinical laboratory sciences, vol. 53, no. 6, 2016, pp. 379-395. https://doi.org/10.1080/10408363.2016.1190682

Foster, Brandon, Timea Balassa, Thomas Benen, Marin Dominović, Gabriel Elmadjian, Violetta Florova, Maite Fransolet, et al. "Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction." Critical reviews in clinical laboratory sciences 53, no. 6 (2016): 379-395. https://doi.org/10.1080/10408363.2016.1190682

Foster, B., et al. (2016) 'Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction', Critical reviews in clinical laboratory sciences, 53(6), pp. 379-395. doi: 10.1080/10408363.2016.1190682

Foster B, Balassa T, Benen T, Dominović M, Elmadjian G, Florova V, and sur.. Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction. Critical reviews in clinical laboratory sciences [Internet]. 2016 [cited 2024 May 12];53(6):379-395. doi: 10.1080/10408363.2016.1190682

B. Foster, et al., "Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction", Critical reviews in clinical laboratory sciences, vol. 53, no. 6, pp. 379-395, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:620875. [Accessed: 12 May 2024]

Metadata
Title (english)Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction
AuthorBrandon Foster
AuthorTimea Balassa
AuthorThomas Benen
AuthorMarin Dominović
AuthorGabriel Elmadjian
AuthorVioletta Florova
AuthorMaite Fransolet
AuthorAndrea Kestlerova
AuthorGabriela Kmiecik
AuthorIrena Kostadinova
AuthorChristiana Kyvelidou
AuthorMatyas Meggyes
AuthorMina Mincheva
AuthorLaura Moro
AuthorJana Pastuschek
AuthorValentina Spoldi
AuthorPetra Wandernoth
AuthorMaja Weber
AuthorBettina Toth
AuthorUdo Markert
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Extracellular vesicles (EVs) are released from almost all cells and tissues. They are able to transport substances (e.g. proteins, RNA or DNA) at higher concentrations than in their environment and may adhere in a receptor- controlled manner to specific cells or tissues in order to release their content into the respective target structure. Blood contains high concentrations of EVs mainly derived from platelets, and, at a smaller amount, from erythrocytes. The female and male reproductive tracts produce EVs which may be associated with fertility or infertility and are released into body fluids and mucosas of the urogenital organs. In this review, the currently relevant detection methods are presented and critically compared. During pregnancy, placenta-derived EVs are dynamically detectable in peripheral blood with changing profiles depending upon progress of pregnancy and different pregnancy- associated pathologies, such as preeclampsia. EVs offer novel non-invasive diagnostic tools which may reflect the situation of the placenta and the fetus. EVs in urine have the potential of reflecting urogenital diseases including cancers of the neighbouring organs. Several methods for detection, quantification and phenotyping of EVs have been established, which include electron microscopy, flow cytometry, ELISA-like methods, Western blotting, and analyses based on Brownian motion. This review article summarises the current knowledge about EVs in blood and cord blood, in the different compartments of the male and female reproductive tract, in trophoblast cells from normal and pre-eclamptic pregnancies, in placenta ex vivo perfusate, in the amniotic fluid, and in breast milk, as well as their potential effects on natural killer (NK) cells as possible targets
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCritical reviews in clinical laboratory sciences
Numberingvol. 53, no. 6, pp. 379-395
p-ISSN1040-8363
DOIhttps://doi.org/10.1080/10408363.2016.1190682
URN:NBNurn:nbn:hr:184:620875
Publication2016
ProjectNumber: 13.06.1.1.06
Title (croatian): Imuno-endokrini mehanizmi na majčino-fetalnom spoju tijekom rane trudnoće
Leader: Daniel Rukavina
Jurisdiction: Croatia
Funding stream: Sveučilište u Rijeci
Document URLhttp://bib.irb.hr/817031
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2022-02-21 12:49:48