prikaz prve stranice dokumenta Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
No public access
Scientific paper - Preliminary note / Short communication
Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
Virus Research, 256 (2018); 90-95. https://doi.org/10.1016/j.virusres.2018.08.002
Cokarić Brdovčak, Maja; Zubković, Andreja; Ferenčić, Antun; Šoša, Ivan; Stemberga, Valter; Cuculić, Dražen; Rokić, Filip; Vugrek, Oliver; Hackenberg, Michael; Jurak, Igor

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Cokarić Brdovčak, M., Zubković, A., Ferenčić, A., Šoša, I., Stemberga, V., Cuculić, D. ... Jurak, I. (2018). Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia. Virus Research, 256., 90-95. doi: 10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, Maja, et al. "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia." Virus Research, vol. 256, 2018, pp. 90-95. https://doi.org/10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, Maja, Andreja Zubković, Antun Ferenčić, Ivan Šoša, Valter Stemberga, Dražen Cuculić, Filip Rokić, Oliver Vugrek, Michael Hackenberg and Igor Jurak. "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia." Virus Research 256 (2018): 90-95. https://doi.org/10.1016/j.virusres.2018.08.002

Cokarić Brdovčak, M., et al. (2018) 'Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia', Virus Research, 256, pp. 90-95. doi: 10.1016/j.virusres.2018.08.002

Cokarić Brdovčak M, Zubković A, Ferenčić A, Šoša I, Stemberga V, Cuculić D, and sur.. Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia. Virus Research [Internet]. 2018 [cited 2024 April 25];256:90-95. doi: 10.1016/j.virusres.2018.08.002

M. Cokarić Brdovčak, et al., "Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia", Virus Research, vol. 256, pp. 90-95, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245977. [Accessed: 25 April 2024]

Metadata
Title (english)Herpes simplex virus 1 miRNA sequence variations in latently infected human trigeminal ganglia
AuthorMaja Cokarić Brdovčak
MBZ: 289090
AuthorAndreja Zubković
MBZ: 367491
AuthorAntun Ferenčić
AuthorIvan Šoša
AuthorValter Stemberga
AuthorDražen Cuculić
AuthorFilip Rokić
MBZ: 373032
AuthorOliver Vugrek
MBZ: 232935
AuthorMichael Hackenberg
AuthorIgor Jurak
MBZ: 229960
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Forensic Medicine and Criminalistics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Human herpes simplex virus 1 (HSV-1) expresses numerous miRNAs, the function of which is not well understood. Several qualitative and quantitative analyses of HSV-1 miRNAs have been performed on infected cells in culture and animal models, however, there is very limited knowledge of their expression in human samples. We sequenced small-RNA libraries of RNA derived from human trigeminal ganglia latently infected with HSV-1 and Varicella zoster virus (VZV) and detected only a small subset of HSV-1 miRNA. The most abundantly expressed miRNAs are miR- H2, miRNA that regulates the expression of immediate early gene ICP0, and miR-H3 and -H4, both miRNAs expressed antisense to the transcript encoding the major neurovirulence factor ICP34.5. The sequence of many HSV-1 miRNAs detected in human samples was different from the sequences deposited in miRBase, which might significantly affect targeted functional analyses.
Keywords (english)
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleVirus Research
Numberingvol. 256, pp. 90-95
p-ISSN0168-1702
DOIhttps://doi.org/10.1016/j.virusres.2018.08.002
URN:NBNurn:nbn:hr:184:245977
Publication2018
ProjectNumber: KK.011.1.01.0006
Title (croatian): Jačanje kapaciteta CerVirVac-a za istraživanja u virusnoj imunologiji i vakcinologiji
Leader: Stipan Jonjić
Jurisdiction: eu
ProjectNumber: N/A
Title (croatian): Centar izvrsnosti za virusnu imunologiju i cjepiva
Title (english): Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines
Acronym: CERVirVac
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZCI
Document URLhttp://bib.irb.hr/950080
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2022-02-22 07:41:38