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Scientific paper - Original scientific paper
Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control
Acta clinica Croatica, 59 (2020), 4; 641-648. https://doi.org/10.20471/acc.2020.59.04.10
Pintarić, Hrvoje; Knezović Florijan, Marijana; Bridges, Ian; Steiner, Robert; Zaputović, Luka; Miličić, Davor

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Pintarić, H., Knezović Florijan, M., Bridges, I., Steiner, R., Zaputović, L. & Miličić, D. (2020). Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control. Acta clinica Croatica, 59. (4), 641-648. doi: 10.20471/acc.2020.59.04.10

Pintarić, Hrvoje, et al. "Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control." Acta clinica Croatica, vol. 59, no. 4, 2020, pp. 641-648. https://doi.org/10.20471/acc.2020.59.04.10

Pintarić, Hrvoje, Marijana Knezović Florijan, Ian Bridges, Robert Steiner, Luka Zaputović and Davor Miličić. "Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control." Acta clinica Croatica 59, no. 4 (2020): 641-648. https://doi.org/10.20471/acc.2020.59.04.10

Pintarić, H., et al. (2020) 'Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control', Acta clinica Croatica, 59(4), pp. 641-648. doi: 10.20471/acc.2020.59.04.10

Pintarić H, Knezović Florijan M, Bridges I, Steiner R, Zaputović L, Miličić D. Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control. Acta clinica Croatica [Internet]. 2020 [cited 2024 November 07];59(4):641-648. doi: 10.20471/acc.2020.59.04.10

H. Pintarić, M. Knezović Florijan, I. Bridges, R. Steiner, L. Zaputović and D. Miličić, "Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control", Acta clinica Croatica, vol. 59, no. 4, pp. 641-648, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:956509. [Accessed: 07 November 2024]

Metadata
Title (english)Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control
AuthorHrvoje Pintarić
MBZ: 224771
AuthorMarijana Knezović Florijan
AuthorIan Bridges
AuthorRobert Steiner
MBZ: 167711
AuthorLuka Zaputović
AuthorDavor Miličić
MBZ: 31460
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Our observational study evaluated current management of elevated low-density lipoprotein cholesterol (LDL-C) in adult secondary prevention patients (all very high risk (VHR) by European guidelines) attending specialist clinics across Croatia. Data were collected retrospectively from patient records for the preceding 12 months. The subset judged to be at extreme risk (ER ; American Association of Clinical Endocrinologists (AACE) criteria ; n=48) were compared with the remaining patients (VHR group ; n=41). All patients were receiving statins (75.6% VHR/81.3% ER at high-intensity), with only a minority receiving concomitant lipid-lowering treatment (7.3% VHR/16.7% ER). Median (Q1, Q3) LDL-C levels at the last visit were 1.9 (1.6, 2.4) mmol/L for VHR and 2.1 (1.5, 3.1) mmol/L for ER, with only 41.5% (95% CI 26.3-57.9) of VHR patients and 27.1% (15.3- 41.9) of ER patients attaining their LDL-C targets (<1.8 mmol/L and <1.42 mmol/L, respectively). Thus, we found that a substantial proportion of VHR and ER secondary prevention patients being treated across Croatia had LDL-C levels exceeding the targets recommended in the European and newer AACE guidelines, but not all were receiving high- intensity statins. Identification of ER patients and their lipid patterns may help optimize usage of high-intensity statin treatment, alone or along with newer treatments, for better control of elevated LDL -C.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 59, no. 4, pp. 641-648
p-ISSN0353-9466
DOIhttps://doi.org/10.20471/acc.2020.59.04.10
URN:NBNurn:nbn:hr:184:956509
Publication2020
Document URLhttp://bib.irb.hr/1144446
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-02-24 13:16:11