prikaz prve stranice dokumenta Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
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Scientific paper - Original scientific paper
Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
International Journal of Pharmacy Practice., 26 (2018), 2; 156-164. https://doi.org/10.1111/ijpp.12383
Van Heerden, JA; Burger, JR; Gerber, JJ; Vlahović‐ Palčevski, Vera.

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Van Heerden, J., Burger, J., Gerber, J. & Vlahović‐ Palčevski, V. (2018). Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.. International Journal of Pharmacy Practice., 26. (2), 156-164. doi: 10.1111/ijpp.12383

Van Heerden, JA, et al. "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.." International Journal of Pharmacy Practice., vol. 26, no. 2, 2018, pp. 156-164. https://doi.org/10.1111/ijpp.12383

Van Heerden, JA, JR Burger, JJ Gerber and Vera. Vlahović‐ Palčevski. "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.." International Journal of Pharmacy Practice. 26, no. 2 (2018): 156-164. https://doi.org/10.1111/ijpp.12383

Van Heerden, J., et al. (2018) 'Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.', International Journal of Pharmacy Practice., 26(2), pp. 156-164. doi: 10.1111/ijpp.12383

Van Heerden J, Burger J, Gerber J, Vlahović‐ Palčevski V. Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.. International Journal of Pharmacy Practice. [Internet]. 2018 [cited 2024 May 12];26(2):156-164. doi: 10.1111/ijpp.12383

J. Van Heerden, J. Burger, J. Gerber and V. Vlahović‐ Palčevski, "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.", International Journal of Pharmacy Practice., vol. 26, no. 2, pp. 156-164, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:724298. [Accessed: 12 May 2024]

Metadata
Title (english)Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
Title (english)International Journal of Pharmacy Practice. 2018 Apr ; 26(2):156-64.
AuthorJA Van Heerden
AuthorJR Burger
AuthorJJ Gerber
AuthorVera. Vlahović‐ Palčevski
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Abstract (english)
Objectives To determine the prevalence of potentially serious drug–drug interactions (DDIs) and their relationship with gender and age, among elderly in South Africa. Methods A cross‐sectional study was conducted using pharmaceutical claims data for 2013, for a total of 103 420 medical scheme beneficiaries’ ≥65 years. All medications dispensed within one calendar month where the days’ supply of medication dispensed overlapped, were grouped as one prescription. DDIs per prescription were then identified using the Mimica Matanović/Vlahović‐Palčevski DDI protocol. Results were interpreted using effect sizes, that is Cramér's V, Cohen's d and Cohen's ƒ2. Key findings A total of 331 659 DDIs were identified on 235 870 (25.8%, N = 912 713) prescriptions (mean 0.36 (SD 0.7) (95% CI, 0.36 to 0.37)). Women encountered 63.5% of all DDIs. Effect sizes for the association between DDIs and age group (Cramér's V = 0.06), and gender (Cramér's V = 0.05) was negligible. There was no difference between men and women regarding the mean number of DDIs identified per prescription (Cohen's d = 0.10). The number of medicine per prescription (ƒ2 = 0.51) was the biggest predictor of the DDIs. The most frequent interacting drug combinations were between central nervous system medicines (30.6%). Conclusion Our study is the first to report the prevalence of potentially serious DDIs among an elderly population in the South African private health sector utilising the Mimica Matanović/Vlahović‐ Palčevski DDI protocol. Overall, we identified DDIs in approximately 26% of the prescriptions in our study. Age and gender were not found to be predictors of potentially serious DDIs.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleInternational Journal of Pharmacy Practice.
Numberingvol. 26, no. 2, pp. 156-164
p-ISSN2042-7174
DOIhttps://doi.org/10.1111/ijpp.12383
URN:NBNurn:nbn:hr:184:724298
Publication2018
Document URLhttp://bib.irb.hr/1033399
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-03-03 16:18:32