prikaz prve stranice dokumenta Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report
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Scientific paper - Case study
Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report
Applied immunohistochemistry & molecular morphology, 24 (2016), 10; e89-e93. https://doi.org/10.1097/PAI.0000000000000361
Jonjić, Nives; Seili-Bekafigo, Irena; Fučkar Čupić, Dora; Lučin, Ksenija; Duletić- Načinović, Antica; Valković, Toni

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Jonjić, N., Seili Bekafigo, I., Fučkar Čupić, D., Lučin, K., Duletić Načinović, A. & Valković, T. (2016). Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report. Applied immunohistochemistry & molecular morphology, 24. (10), e89-e93. doi: 10.1097/PAI.0000000000000361

Jonjić, Nives, et al. "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report." Applied immunohistochemistry & molecular morphology, vol. 24, no. 10, 2016, pp. e89-e93. https://doi.org/10.1097/PAI.0000000000000361

Jonjić, Nives, Irena Seili Bekafigo, Dora Fučkar Čupić, Ksenija Lučin, Antica Duletić Načinović and Toni Valković. "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report." Applied immunohistochemistry & molecular morphology 24, no. 10 (2016): e89-e93. https://doi.org/10.1097/PAI.0000000000000361

Jonjić, N., et al. (2016) 'Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report', Applied immunohistochemistry & molecular morphology, 24(10), pp. e89-e93. doi: 10.1097/PAI.0000000000000361

Jonjić N, Seili Bekafigo I, Fučkar Čupić D, Lučin K, Duletić Načinović A, Valković T. Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report. Applied immunohistochemistry & molecular morphology [Internet]. 2016 [cited 2024 May 07];24(10):e89-e93. doi: 10.1097/PAI.0000000000000361

N. Jonjić, I. Seili Bekafigo, D. Fučkar Čupić, K. Lučin, A. Duletić Načinović and T. Valković, "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report", Applied immunohistochemistry & molecular morphology, vol. 24, no. 10, pp. e89-e93, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:846403. [Accessed: 07 May 2024]

Metadata
Title (english)Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report
AuthorNives Jonjić
AuthorIrena Seili-Bekafigo
AuthorDora Fučkar Čupić
AuthorKsenija Lučin
AuthorAntica Duletić- Načinović
AuthorToni Valković
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Simultaneous occurrence of T-cell and B-cell neoplasms is rare and etiologic relationships between these two malignancies are poorly understood. We describe a case of 66-year-old woman who was admitted to the hospital because of fever, hemoptysis, lymphadenopathy, and skin rash. Enlarged lymph nodes in the axillary, pectoral, paratracheal and periportal regions, as well as slight hepato- and splenomegaly were confirmed. Peripheral blood smear revealed rouleaux formation and numerous circulating plasma cells, with plasmacytoid lymphocytes. Immunofixation- electrophoresis detected a monoclonal band defined as IgG-lambda light chains with broad band polyclonal IgA. The patient died from abrupt splenic rupture before diagnostic work-up was finished. Postmortem examination revealed infiltration of atypical lymphoid cells exhibiting high proliferative activity admixed with typical and atypical plasma cells in several organs. Thus plasma cell leukemia (IgG-lambda) as a rare and aggressive variant of plasma cell myeloma in present case was associated with aggressive peripheral T cell lymphoma and polyclonal (IgA) plasmacytosis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionSubmitted version
Journal titleApplied immunohistochemistry & molecular morphology
Numberingvol. 24, no. 10, pp. e89-e93
p-ISSN1541-2016
DOIhttps://doi.org/10.1097/PAI.0000000000000361
URN:NBNurn:nbn:hr:184:846403
Publication2016
Document URLhttp://bib.irb.hr/813361
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-03-04 12:09:05