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Scientific paper - Original scientific paper
The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey
Advances in Therapy, 34 (2017), 8; 2043-2057. https://doi.org/10.1007/s12325-017-0589-5
Potpara, Tatjana S.; Trendafilova, Elina; Dan, Gheorghe-Andrei; Goda, Artan; Kusljugic, Zumreta; Manola, Sime; Music, Ljilja; Gjini, Viktor; Pojskic, Belma; Popescu, Mircea Ioakim; Georgescu, Catalina Arsenescu; Dimitrova, Elena S.; Kamenova, Delyana; Ekmeciu, Uliks; Mrsic, Denis; Nenezic, Ana; Brusich, Sandro; Milanov, Srdjan; Zeljkovic, Ivan; Lip, Gregory Y. H. More authors...

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Potpara, T. S., Trendafilova, E., Dan, G. A., Goda, A., Kusljugic, Z., Manola, S. ... Lip, G. Y. H. (2017). The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey. Advances in Therapy, 34. (8), 2043-2057. doi: 10.1007/s12325-017-0589-5

Potpara, Tatjana S., et al. "The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey." Advances in Therapy, vol. 34, no. 8, 2017, pp. 2043-2057. https://doi.org/10.1007/s12325-017-0589-5

Potpara, Tatjana S., Elina Trendafilova, Gheorghe Andrei Dan, Artan Goda, Zumreta Kusljugic, Sime Manola, Ljilja Music, et al. "The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey." Advances in Therapy 34, no. 8 (2017): 2043-2057. https://doi.org/10.1007/s12325-017-0589-5

Potpara, T. S., et al. (2017) 'The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey', Advances in Therapy, 34(8), pp. 2043-2057. doi: 10.1007/s12325-017-0589-5

Potpara TS, Trendafilova E, Dan GA, Goda A, Kusljugic Z, Manola S, and sur.. The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey. Advances in Therapy [Internet]. 2017 [cited 2025 January 02];34(8):2043-2057. doi: 10.1007/s12325-017-0589-5

T. S. Potpara, et al., "The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey", Advances in Therapy, vol. 34, no. 8, pp. 2043-2057, 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:987609. [Accessed: 02 January 2025]

Metadata
Title (english)The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey
AuthorTatjana S. Potpara
AuthorElina Trendafilova
AuthorGheorghe-Andrei Dan
AuthorArtan Goda
AuthorZumreta Kusljugic
AuthorSime Manola
AuthorLjilja Music
AuthorViktor Gjini
AuthorBelma Pojskic
AuthorMircea Ioakim Popescu
AuthorCatalina Arsenescu Georgescu
AuthorElena S. Dimitrova
AuthorDelyana Kamenova
AuthorUliks Ekmeciu
AuthorDenis Mrsic
AuthorAna Nenezic
AuthorSandro Brusich
AuthorSrdjan Milanov
AuthorIvan Zeljkovic
AuthorGregory Y. H. Lip
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Surgery)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract (english)
Abstract Introduction: Data on management of atrial fibrillation (AF) in the Balkan Region are scarce. To capture the patterns in AF management in contemporary clinical practice in the Balkan countries a prospective survey was conducted between December 2014 and February 2015, and we report results pertinent to the use of non-vitamin K antagonist oral anticoagulants (NOACs). Methods: A 14-week prospective, multicenter survey of consecutive AF patients seen by cardiologists or internal medicine specialists was conducted in Albania, Bosnia and Herzegovina, Bulgaria, Croatia, Montenegro, Romania, and Serbia (a total of about 50 million inhabitants). Results: Of 2712 enrolled patients, 2663 (98.2%) had complete data relevant to oral anticoagulant (OAC) use (mean age 69.1 ± 10.9 years, female 44.6%). Overall, OAC was used in 1960 patients (73.6%) of whom 338 (17.2%) received NOACs. Malignancy [odds ratio (OR), 95% confidence interval (CI) 2.06, 1.20-3.56], rhythm control (OR 1.64, 1.25-2.16), and treatment by cardiologists were independent predictors of NOAC use (OR 2.32, 1.51-3.54) [all p < 0.01)], whilst heart failure and valvular disease were negatively associated with NOAC use (both p < 0.01). Individual stroke and bleeding risk were not significantly associated with NOAC use on multivariate analysis. Conclusions: NOACs are increasingly used in AF patients in the Balkan Region, but NOAC use is predominantly guided by factors other than evidence-based decision-making (e.g., drug availability on the market or reimbursement policy). Efforts are needed to establish an evidence-based approach to OAC selection and to facilitate the optimal use of OAC, thus improving the outcomes in AF patients in this large region.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAdvances in Therapy
Numberingvol. 34, no. 8, pp. 2043-2057
p-ISSN0741-238X
e-ISSN1865-8652
DOIhttps://doi.org/10.1007/s12325-017-0589-5
URN:NBNurn:nbn:hr:184:987609
Publication2017
Document URLhttp://link.springer.com/10.1007/s12325-017-0589-5
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2022-03-11 13:41:59