prikaz prve stranice dokumenta Murine model of pregnancy-associated infection
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Scientific paper - Review paper
Murine model of pregnancy-associated infection
FEMS Immunology & Medical Microbiology, 35 (2003), 3; 177-182. https://doi.org/10.1016/S0928-8244(02)00449-2
Abram, Maja; Schlueter, Dirk; Vučković, Darinka; Wraber, Branka; Dorić, Miljenko; Deckert, Martina

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Abram, M., Schlueter, D., Vučković, D., Wraber, B., Dorić, M. & Deckert, M. (2003). Murine model of pregnancy-associated infection. FEMS Immunology & Medical Microbiology, 35. (3), 177-182. doi: 10.1016/S0928-8244(02)00449-2

Abram, Maja, et al. "Murine model of pregnancy-associated infection." FEMS Immunology & Medical Microbiology, vol. 35, no. 3, 2003, pp. 177-182. https://doi.org/10.1016/S0928-8244(02)00449-2

Abram, Maja, Dirk Schlueter, Darinka Vučković, Branka Wraber, Miljenko Dorić and Martina Deckert. "Murine model of pregnancy-associated infection." FEMS Immunology & Medical Microbiology 35, no. 3 (2003): 177-182. https://doi.org/10.1016/S0928-8244(02)00449-2

Abram, M., et al. (2003) 'Murine model of pregnancy-associated infection', FEMS Immunology & Medical Microbiology, 35(3), pp. 177-182. doi: 10.1016/S0928-8244(02)00449-2

Abram M, Schlueter D, Vučković D, Wraber B, Dorić M, Deckert M. Murine model of pregnancy-associated infection. FEMS Immunology & Medical Microbiology [Internet]. 2003 April [cited 2024 November 30];35(3):177-182. doi: 10.1016/S0928-8244(02)00449-2

M. Abram, D. Schlueter, D. Vučković, B. Wraber, M. Dorić and M. Deckert, "Murine model of pregnancy-associated infection", FEMS Immunology & Medical Microbiology, vol. 35, no. 3, pp. 177-182, April 2003. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:802530. [Accessed: 30 November 2024]

Metadata
Title (english)Murine model of pregnancy-associated infection
AuthorMaja Abram
AuthorDirk Schlueter
AuthorDarinka Vučković
AuthorBranka Wraber
AuthorMiljenko Dorić
AuthorMartina Deckert
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
Listeria monocytogenes has been recognized as a significant pathogen, occurring worldwide, capable of causing animal and human infections. In its most severe form, listeriosis is an invasive disease that affects immunocompromised patients. Additionally, pregnant women represent a high-risk group for L. monocytogenes infection. Abortion, stillbirth or severe neonatal infection can be the serious outcome of such an infection. In an experimental murine model of pregnancy-associated listeriosis we studied the impact of L. monocytogenes on the maternal immune response and pregnancy outcome. In comparison to virgin animals, pregnant mice mounted lower levels of protective cytokines and were unable to eliminate the pathogen. The impaired maternal immune response that has been found both on the systemic and local level, facilitated bacterial multiplication in the liver, placenta and ultimately in the fetal tissues. This resulted in severe necrotizing hemorrhagic hepatitis and Listeria-induced placental necrosis, increasing the incidence of postimplantation loss and poor pregnancy outcome.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFEMS Immunology & Medical Microbiology
Numberingvol. 35, no. 3, pp. 177-182
p-ISSN0928-8244
e-ISSN1574-695X
DOIhttps://doi.org/10.1016/S0928-8244(02)00449-2
URN:NBNurn:nbn:hr:184:802530
Publication2003-04
Document URLhttps://academic.oup.com/femspd/article-lookup/doi/10.1016/S0928-8244(02)00449-2
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2022-03-17 22:08:36