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Scientific paper - Original scientific paper
Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences
Collegium antropologicum, 35 (2011), 2; 483-486. urn:nbn:hr:184:568770
Antončić, Igor; Dunatov, Siniša; Bralić, Marina; Perković, Olivio; Čoklo, Miran; Jurjević, Ante

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Antončić, I., Dunatov, S., Bralić, M., Perković, O., Čoklo, M. & Jurjević, A. (2011). Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences. Collegium antropologicum, 35. (2), 483-486. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:568770

Antončić, Igor, et al. "Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences." Collegium antropologicum, vol. 35, no. 2, 2011, pp. 483-486. https://urn.nsk.hr/urn:nbn:hr:184:568770

Antončić, Igor, Siniša Dunatov, Marina Bralić, Olivio Perković, Miran Čoklo and Ante Jurjević. "Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences." Collegium antropologicum 35, no. 2 (2011): 483-486. https://urn.nsk.hr/urn:nbn:hr:184:568770

Antončić, I., et al. (2011) 'Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences', Collegium antropologicum, 35(2), pp. 483-486. Available at: https://urn.nsk.hr/urn:nbn:hr:184:568770 (Accessed 11 May 2024)

Antončić I, Dunatov S, Bralić M, Perković O, Čoklo M, Jurjević A. Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences. Collegium antropologicum [Internet]. 2011 [cited 2024 May 11];35(2):483-486. Available at: https://urn.nsk.hr/urn:nbn:hr:184:568770

I. Antončić, S. Dunatov, M. Bralić, O. Perković, M. Čoklo and A. Jurjević, "Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences", Collegium antropologicum, vol. 35, no. 2, pp. 483-486, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:568770. [Accessed: 11 May 2024]

Metadata
Title (english)Intravenous Thrombolysis for Acute Ischemic Stroke – Our Experiences
AuthorIgor Antončić
AuthorSiniša Dunatov
AuthorMarina Bralić
AuthorOlivio Perković
AuthorMiran Čoklo
AuthorAnte Jurjević
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Neurology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Forensic Medicine and Criminalistics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Intravenous (IV) thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the only available pharmacological therapy to improve the outcome of acute ischemic stroke. We compared 71 patients presenting with ischaemic stroke and given intravenous rt-PA (0·9 mg/kg total dose) within 3 h with 71 patients who present to the hospital more than 3 hours after stroke symptom onset. The primary endpoint was the modified Rankin scale (mRS) at 90 days, dichotomised for favourable and unfavourable (score 2–6). Outcome measures were symptomatic intracerebral haemorrhage within 36 h (haemorrhage associated with National Institutes of Health Stroke Scale [NIHSS] 4 points deterioration), and mortality at 3 months. More patients had favourable outcome with the rt-PA-treated group than with the control group (64.79% vs. 22.54%; p= 0.0001). The greater proportion of patients left with minimal or no deficit 90 days after rt-PA treatment, as compared with the control group. In the treated group symptomatic intracranial hemorrhage occurred in 1 patient who recovered to a level of functional independence, and asymptomatic intracranial hemorrhage was observed in 2 patients. Our experience of an acute stroke thrombolysis service shows that we are able to provide this treatment safely and in accordance with established treatment guidelines. We recommend thrombolytic treatment in acute ischemic stroke for selected population.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 35, no. 2, pp. 483-486
p-ISSN0350-6134
e-ISSN1848-9486
URN:NBNurn:nbn:hr:184:568770
Publication2011
Document URLhttps://hrcak.srce.hr/69132
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-03-18 13:27:05