prikaz prve stranice dokumenta Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma
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Scientific paper - Original scientific paper
Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma
Reports of Practical Oncology and Radiotherapy, 27 (2022), 1; 86-96. https://doi.org/10.5603/RPOR.a2022.0013
Švabić Kolacio, Manda; Rajlić, David; Radojčić, Milan; Smilović Radojčić, Đeni; Obajdin, Nevena; Dundara Debeljuh, Dea; Jurković, Slaven

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Švabić Kolacio, M., Rajlić, D., Radojčić, M., Smilović Radojčić, Đ., Obajdin, N., Dundara Debeljuh, D. & Jurković, S. (2022). Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma. Reports of Practical Oncology and Radiotherapy, 27. (1), 86-96. doi: 10.5603/RPOR.a2022.0013

Švabić Kolacio, Manda, et al. "Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma." Reports of Practical Oncology and Radiotherapy, vol. 27, no. 1, 2022, pp. 86-96. https://doi.org/10.5603/RPOR.a2022.0013

Švabić Kolacio, Manda, David Rajlić, Milan Radojčić, Đeni Smilović Radojčić, Nevena Obajdin, Dea Dundara Debeljuh and Slaven Jurković. "Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma." Reports of Practical Oncology and Radiotherapy 27, no. 1 (2022): 86-96. https://doi.org/10.5603/RPOR.a2022.0013

Švabić Kolacio, M., et al. (2022) 'Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma', Reports of Practical Oncology and Radiotherapy, 27(1), pp. 86-96. doi: 10.5603/RPOR.a2022.0013

Švabić Kolacio M, Rajlić D, Radojčić M, Smilović Radojčić Đ, Obajdin N, Dundara Debeljuh D, and sur.. Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma. Reports of Practical Oncology and Radiotherapy [Internet]. 2022 [cited 2024 May 18];27(1):86-96. doi: 10.5603/RPOR.a2022.0013

M. Švabić Kolacio, et al., "Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma", Reports of Practical Oncology and Radiotherapy, vol. 27, no. 1, pp. 86-96, 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:442554. [Accessed: 18 May 2024]

Metadata
Title (english)Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non- small cell lung carcinoma
AuthorManda Švabić Kolacio
AuthorDavid Rajlić
AuthorMilan Radojčić
MBZ: 237933
AuthorĐeni Smilović Radojčić
MBZ: 382732
AuthorNevena Obajdin
AuthorDea Dundara Debeljuh
AuthorSlaven Jurković
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Medical Physics and Biophysics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Biophysics and Medical Physics
Abstract (english)
Background: Study determines differences in calculated dose distributions for Non-Small Cell Lung Carcinoma (NSCLC) patients. NSCLC cases were investigated, NSCLC being the most common lung cancer treated by radiotherapy in our clinical practice. Materials and methods: A retrospective study of 15 NSCLC patient dose distributions originally calculated using standard superposition (SS) and recalculated using collapsed cone (CC) and Monte Carlo (MC) based algorithm expressed as dose to medium in medium (MCDm) and dose to water in medium (MCDw, ) was performed so that prescribed dose covers at least 99% of the gross target volume (GTV). Statistical analysis was performed for differences of conformity index (CI), heterogeneity index (HI), gradient index (GI), dose delivered to 2% of the volume (D2%), mean dose (Dmean) and percentage of volumes covered by prescribed dose (V70Gy). For organs at risk (OARs), Dmean and percentage of volume receiving 20 Gy and 5Gy (V20Gy, V5Gy) were analysed. Results: Statistically significant difference for GTVs was observed between MCDw and SS algorithm in mean dose only. For planning target volumes (PTVs), statistically significant differences were observed in prescribed dose coverage for CC, MCDm and MCDw. The differences in mean CI value for the CC algorithm and mean HI value for MCDm and MCDw were statistically significant. There is a statistically significant difference in the number of MUs for MCDm and MCDw compared to SS. Conclusion: All investigated algorithms succeed in managing the restrictive conditions of the clinical goals. This study shows the drawbacks of the CC algorithm compared to other algorithms used.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleReports of Practical Oncology and Radiotherapy
Numberingvol. 27, no. 1, pp. 86-96
p-ISSN1507-1367
DOIhttps://doi.org/10.5603/RPOR.a2022.0013
URN:NBNurn:nbn:hr:184:442554
Publication2022
Document URLhttp://bib.irb.hr/1180476
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-04-07 12:32:50