Aortic stenosis is a valvular heart disease caused by changes in the leaflets of the aortic valve. These changes result in narrowing of the aortic orifice and consequent obstruction of systolic blood flow from the left ventricle to the aorta. The prevalence of the disease increases with age, and the most common causes are degenerative changes in the aortic valve, congenital bicuspid valve and rheumatic fever. Three main symptoms are shortness of breath, chest pain and syncope, and the gold standard for diagnosis is transthoracic echocardiography. The disease is usually asymptomatic for a long time, and once the symptoms appear, it is necessary to recognize them in time manner and start of the treatment. The only long-term successful therapeutic option for the symptomatic stage of the disease is aortic valve replacement. This can be done by classic cardiac surgery or by transcatheter aortic valve implantation (TAVI). Candidates for TAVI are patients at high surgical operative risk or with contraindication for surgery. Preprocedural testing includes routine blood tests, ECG and imaging. TAVI is most commonly performed by retrograde arterial transfemoral route under local anesthesia with moderate sedation, and the two available types of technologies are balloon expanding and self-expanding systems. Complications of TAVI include periprocedural complications and long-term complications. Post-procedural care includes follow-up of valve function and active search for potential complications. Patients are given antithrombotic therapy and educated about importance of infective endocarditis prophylaxis.