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master's thesis
Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi
Rijeka: University of Rijeka, Faculty of Medicine, 2022. urn:nbn:hr:184:450262
Kinkela, Fran
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Kinkela, F. (2022). Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:450262

Kinkela, Fran. "Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:450262

Kinkela, Fran. "Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:450262

Kinkela, F. (2022). 'Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 02 May 2024, https://urn.nsk.hr/urn:nbn:hr:184:450262

Kinkela F. Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2022 [cited 2024 May 02] Available at: https://urn.nsk.hr/urn:nbn:hr:184:450262

F. Kinkela, "Indikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:184:450262

Metadata
TitleIndikacije i ishod liječenja ugradbenim kardioverter defibrilatorom u kliničkoj praksi
Title (english)Implantable Cardioverter Defibrillator (ICD) in Clinical Practice - Indications and Outcomes
AuthorFran Kinkela
MentorTeodora Zaninović Jurjević (mentor)
Committee memberIvan Bubić (predsjednik povjerenstva)
Committee memberVjekoslav Tomulić (član povjerenstva)
Committee memberZlatko Čubranić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Ugradbeni kardioverter defibrilator (ICD) služi kao direktna terapijska metoda u svrhu prevencije nagle srčane smrti. Izuzev funkcije prekida ventrikularnih malignih aritmija, sadrži funkcije elektrostimulacije te zapisa aritmija. Istražili smo opće karakteristike te rizične faktore u populaciji s ugrađenim ugradbenim kardioverter defibrilatorom tijekom dvogodišnjeg perioda te u dvogodišnjem praćenju uspostavili povezanost rizičnih faktora te aktivacije uređaja i ukupnog mortaliteta. Aktivacija uređaja podrazumijeva šok ili ATP. Žene su znatno manje zastupljene u primaoca uređaja (14,9%). Biventrikularna stimulacija povezana je s manjom učestalošću aktivacije uređaja (p<0,01). Ejekcijska frakcija, fibrilacija atrija, infarkt miokarda, kronična bubrežna bolest i pušenje nisu pokazali povezanost s povišenim aktivacijama uređaja, dok šećerna bolest jest (p<0,05). Popratna medikamentna terapija uz terapiju uređajem analizirana je te također ne pokazuje statistički značajnu povezanost s aktivacijom uređaja. Ukupni mortalitet ispitanika u studiji iznosi 9,5% te skupina s aktivacijom uređaja pokazuje nesignifikantno kraće preživljenje.
Abstract (english)
Implantable cardioverter defibrillator (ICD) serves as a direct therapeutic method for the prevention of sudden cardiac death. In addition to the function of interrupting ventricular malignant arrhythmias, it works as pacemaker and arrhythmia recorder. We investigated the general characteristics and risk factors in the population with an implanted cardioverter defibrillator during a 2-year period, and in a 2-year follow-up we established the connection between risk factors and device activation, as well total mortality. Device activation was assessed as shock or ATP. Women were considerately less represented in device implantation (14,9%). Biventricular stimulation was associated with a lower frequency of device activation (p <0.01). Ejection fraction, atrial fibrillation, myocardial infarction, chronic kidney disease and smoking did not show an association with increased device activations, while diabetes did (p <0.05). Concomitant drug therapy with device therapy has been analysed and also does not show a statistically significant association with device activation. The overall mortality of the subjects in the study was 9.5% and the group with device activation showed insignificantly poorer survival.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:450262
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-07-11 17:10:31