prikaz prve stranice dokumenta Basic principles in surgical treatment of gynecologic malignancies
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Professional paper - Review paper
Basic principles in surgical treatment of gynecologic malignancies
Libri Oncologici : Croatian Journal of Oncology, 34 (2006), 1-3; 29-34. urn:nbn:hr:184:542052
Haller, Herman; Rupčić, Stanislav; Stamatović, Miroslav; Mamula, Ozren; Gobić, Jasna

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Haller, H., Rupčić, S., Stamatović, M., Mamula, O. & Gobić, J. (2006). Basic principles in surgical treatment of gynecologic malignancies. Libri Oncologici : Croatian Journal of Oncology, 34. (1-3), 29-34. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:542052

Haller, Herman, et al. "Basic principles in surgical treatment of gynecologic malignancies." Libri Oncologici : Croatian Journal of Oncology, vol. 34, no. 1-3, 2006, pp. 29-34. https://urn.nsk.hr/urn:nbn:hr:184:542052

Haller, Herman, Stanislav Rupčić, Miroslav Stamatović, Ozren Mamula and Jasna Gobić. "Basic principles in surgical treatment of gynecologic malignancies." Libri Oncologici : Croatian Journal of Oncology 34, no. 1-3 (2006): 29-34. https://urn.nsk.hr/urn:nbn:hr:184:542052

Haller, H., et al. (2006) 'Basic principles in surgical treatment of gynecologic malignancies', Libri Oncologici : Croatian Journal of Oncology, 34(1-3), pp. 29-34. Available at: https://urn.nsk.hr/urn:nbn:hr:184:542052 (Accessed 04 May 2024)

Haller H, Rupčić S, Stamatović M, Mamula O, Gobić J. Basic principles in surgical treatment of gynecologic malignancies. Libri Oncologici : Croatian Journal of Oncology [Internet]. 2006 [cited 2024 May 04];34(1-3):29-34. Available at: https://urn.nsk.hr/urn:nbn:hr:184:542052

H. Haller, S. Rupčić, M. Stamatović, O. Mamula and J. Gobić, "Basic principles in surgical treatment of gynecologic malignancies", Libri Oncologici : Croatian Journal of Oncology, vol. 34, no. 1-3, pp. 29-34, 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:542052. [Accessed: 04 May 2024]

Metadata
Title (english)Basic principles in surgical treatment of gynecologic malignancies
Title (croatian)Temeljna načela kirurškog liječenja zloćudnih ginekoloških novotvorina
AuthorHerman Haller
AuthorStanislav Rupčić
AuthorMiroslav Stamatović
AuthorOzren Mamula
AuthorJasna Gobić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Gynaecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
In the treatment of gynecologic malignancies surgery represents a cornerstone of gynecologic oncology. Surgery is important to establish the definitive diagnosis, to define the extent of disease and to eliminate the tumor according to the type and localization. The most frequent tumors among gynecologic malignancies are cervical, endometrial and ovarian cancer. Actual surgical approach in early cervical cancer with microscopic extension includes conservative techniques, in the first place the use of conisation. In the same group of patients but with fulfilled reproductive activities, hysterectomy is recommended. Radical surgery could be applied in invasive cervical cancer staged IB1 to IIA. Surgical treatment in the advanced stage of cervical cancer could be exerted exclusively in controlled trials as a part of multimodal treatment. Endometrial cancer still remains incompletely defined in the extension of surgical procedures. Namely, lymphadenectomy in patients with endometrial cancer according to the low rate of lymphatic dissemination is not completely accepted in hospital daily practice. Furthermore, the increasing use of minimal invasive surgery transforms our way of thinking, especially in the case of endometrial cancer. Ovarian cancer still remains an unresolved diagnostic problem with negative implication in the treatment efficacy. About two thirds of patients are in advanced stage at the time of their first surgery, primarily for the lack of a high effective screening test as well as unknown pathophysiology in early ovarian cancer development. In early ovarian cancer comprehensive staging should be done, while in patients with advanced disease standard approach should include maximal effort in surgical cytoreduction.
Abstract (croatian)
Kirurški tretman malignih novotvorina ženskog spolnog sustava predstavlja početak i osnovu svakog onkološkog liječenja. Kirurški je zahvat, naime, od temeljne važnosti pri postavljanju konačne dijagnoze, određivanju stadija bolesti, kao i za uklanjanje tumorske mase tijekom prvog operacijskog zahvata sukladno lokalizaciji i vrsti malignoma. Najčešću pojavnost malignoma ženskih spolnih organa nalazimo na cerviksu, endometriju i ovariju. Suvremeni kirurški pristup liječenju ranog stadija - mikroskoposkog raka vrata maternice uključuje konzervativne zahvate u smislu konizacije. U slučajevima gdje je reprodukcija završena može se posegnuti za histerektomijom. Radikalna kirurgija predstavlja metodu izbora u klinički invazivnom obliku bolesti (stadij IB1 do IIA). Kirurško liječenje viših stadija može se rabiti u kontroliranim studijama u sklopu multimodalnog liječenja. Rak endometrija i dalje ostaje u određenom smislu nedovoljno definiran u smislu opsežnosti samoga kirurškog zahvata. Naime, limfadenektomija kod bolesnica s rakom endometrija s obzirom na relativno nisku stopu limfogenog rasapa i dalje predstavlja kamen spoticanja u kliničkoj praksi. S druge strane, sve opsežnije uvođenje endoskopske kirurgije otvorilo je nepovratni put ka prihvaćanju operativnih zahvata s minimalno invazivnim tehnikama. Rak jajnika još uvijek predstavlja veliki dijagnostički i terapijski problem. Kako ne postoje široko primijenjeni učinkoviti testovi probira, bolest se u dvije trećine bolesnica otkriva tek u uznapredovaloj fazi s posljedičnom visokom stopom smrtnosti koja premašuje zbroj smrtnosti svih preostalih ginekoloških malignoma. U bolesnica s naizgled ranim stadijem bolesti potrebno je učiniti sveobuhvatni kirurški zahvat radi određivanja točnog stadija bolesti, dok u bolesnica s uznapredovalom bolešću standardni pristup uključuje optimalnu kiruršku citoredukciju.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleLibri Oncologici : Croatian Journal of Oncology
Numberingvol. 34, no. 1-3, pp. 29-34
p-ISSN0300-8142
e-ISSN2584-3826
URN:NBNurn:nbn:hr:184:542052
Publication2006
Document URLhttps://hrcak.srce.hr/281497
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-08-26 07:21:49