prikaz prve stranice dokumenta Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
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Scientific paper - Review paper
Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
Antibiotics, 11 (2022), 8; 1105. https://doi.org/10.3390/antibiotics11081105
Repac Antić, Davorka; Parčina, Marijo; Gobin, Ivana; Petković Didović, Mirna

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Repac Antić, D., Parčina, M., Gobin, I. & Petković Didović, M. (2022). Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond. Antibiotics, 11. (8). doi: 10.3390/antibiotics11081105

Repac Antić, Davorka, et al. "Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond." Antibiotics, vol. 11, no. 8, 2022. https://doi.org/10.3390/antibiotics11081105

Repac Antić, Davorka, Marijo Parčina, Ivana Gobin and Mirna Petković Didović. "Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond." Antibiotics 11, no. 8 (2022). https://doi.org/10.3390/antibiotics11081105

Repac Antić, D., et al. (2022) 'Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond', Antibiotics, 11(8). doi: 10.3390/antibiotics11081105

Repac Antić D, Parčina M, Gobin I, Petković Didović M. Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond. Antibiotics [Internet]. 2022 August 15 [cited 2024 May 03];11(8). doi: 10.3390/antibiotics11081105

D. Repac Antić, M. Parčina, I. Gobin and M. Petković Didović, "Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond", Antibiotics, vol. 11, no. 8, August 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:580613. [Accessed: 03 May 2024]

Metadata
Title (english)Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
AuthorDavorka Repac Antić
AuthorMarijo Parčina
AuthorIvana Gobin
AuthorMirna Petković Didović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Medical Biochemistry
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Abstract (english)
In the era of escalating antimicrobial resistance, the need for antibacterial drugs with novel or improved modes of action (MOAs) is a health concern of utmost importance. Adding or improving the chelating abilities of existing drugs or finding new, nature-inspired chelating agents seems to be one of the major ways to ensure progress. This review article provides insight into the modes of action of antibacterial agents, class by class, through the perspective of chelation. We covered a wide scope of antibacterials, from a century-old quintessential chelating agent nitroxoline, currently unearthed due to its newly discovered anticancer and antibiofilm activities, over the commonly used antibacterial classes, to new cephalosporin cefiderocol and a potential future class of tetramates. We show the impressive spectrum of roles that chelation plays in antibacterial MOAs. This, by itself, demonstrates the importance of understanding the fundamental chemistry behind such complex processes.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAntibiotics
Numberingvol. 11, no. 8, 1105
e-ISSN2079-6382
DOIhttps://doi.org/10.3390/antibiotics11081105
URN:NBNurn:nbn:hr:184:580613
Publication2022-08-15
Document URLhttps://www.mdpi.com/2079-6382/11/8/1105
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-09-06 13:22:43