prikaz prve stranice dokumenta Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment
  Download
PDF 705.81 KB
Professional paper - Review paper
Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment
Digestive Diseases, 30 (2012), 2; 158-162. https://doi.org/10.1159/000336669
Milić, Sandra; Štimac, Davor

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Milić, S. & Štimac, D. (2012). Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment. Digestive Diseases, 30. (2), 158-162. doi: 10.1159/000336669

Milić, Sandra and Davor Štimac. "Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment." Digestive Diseases, vol. 30, no. 2, 2012, pp. 158-162. https://doi.org/10.1159/000336669

Milić, Sandra and Davor Štimac. "Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment." Digestive Diseases 30, no. 2 (2012): 158-162. https://doi.org/10.1159/000336669

Milić, S. and Štimac, D. (2012) 'Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment', Digestive Diseases, 30(2), pp. 158-162. doi: 10.1159/000336669

Milić S, Štimac D. Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment. Digestive Diseases [Internet]. 2012 [cited 2024 May 13];30(2):158-162. doi: 10.1159/000336669

S. Milić and D. Štimac, "Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment", Digestive Diseases, vol. 30, no. 2, pp. 158-162, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:715077. [Accessed: 13 May 2024]

Metadata
Title (english)Nonalcoholic fatty liver disease/steatohepatitis : Epidemiology, pathogenesis, clinical presentation and treatment
Title (english)Nonalcoholic fatty liver disease/steatohepatitis: Epidemiology, pathogenesis, clinical presentation and treatment
AuthorSandra Milić
AuthorDavor Štimac
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic hepatic disorder in Western countries, with a prevalence of 20-30%. NAFLD comprises 'silent liver disease', in which simple steatosis is the only histological finding and which is benign in course, and nonalcoholic steatohepatitis, which is characterized by hepatocellular injury and inflammation with or without fibrosis. NAFLD is clinically important, because even benign fatty liver can progress to steatohepatitis in many patients, which can lead to liver cirrhosis and its complications and hepatocellular carcinoma. NAFLD is a hepatic manifestation of metabolic syndrome ; it is closely related to other clinical features of metabolic syndrome, and thus to cardiovascular morbidity. There are several different noninvasive techniques for formal diagnosis and follow-up, but liver biopsy remains the gold standard. The most important therapeutic strategies include lifestyle changes, including changes in dietary habits aimed at weight loss and blood pressure regulation, with a consequent decrease in insulin resistance. For some patients with NAFLD/nonalcoholic steatohepatitis, pharmacological treatment is the best option, although further studies are needed to confirm its efficacy and tolerability.
Keywords (english)
Languageenglish
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleDigestive Diseases
Numberingvol. 30, no. 2, pp. 158-162
p-ISSN0257-2753
e-ISSN1421-9875
DOIhttps://doi.org/10.1159/000336669
URN:NBNurn:nbn:hr:184:715077
Publication2012
Document URLhttp://bib.irb.hr/586965
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2022-09-19 13:26:13