prikaz prve stranice dokumenta Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density
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Scientific paper - Original scientific paper
Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density
Cornea, 41 (2022), 10; 1255-1259. https://doi.org/10.1097/ICO.0000000000002917
Antičić-Eichwalder, Marija; Lex, Susanne; Sarny, Stephanie; Schweighofer, Jakob; Marić, Ivana; El-Shabrawi, Yosuf

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Antičić Eichwalder, M., Lex, S., Sarny, S., Schweighofer, J., Marić, I. & El Shabrawi, Y. (2022). Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density. Cornea, 41. (10), 1255-1259. doi: 10.1097/ICO.0000000000002917

Antičić Eichwalder, Marija, et al. "Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density." Cornea, vol. 41, no. 10, 2022, pp. 1255-1259. https://doi.org/10.1097/ICO.0000000000002917

Antičić Eichwalder, Marija, Susanne Lex, Stephanie Sarny, Jakob Schweighofer, Ivana Marić and Yosuf El Shabrawi. "Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density." Cornea 41, no. 10 (2022): 1255-1259. https://doi.org/10.1097/ICO.0000000000002917

Antičić Eichwalder, M., et al. (2022) 'Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density', Cornea, 41(10), pp. 1255-1259. doi: 10.1097/ICO.0000000000002917

Antičić Eichwalder M, Lex S, Sarny S, Schweighofer J, Marić I, El Shabrawi Y. Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density. Cornea [Internet]. 2022 October [cited 2024 April 29];41(10):1255-1259. doi: 10.1097/ICO.0000000000002917

M. Antičić Eichwalder, S. Lex, S. Sarny, J. Schweighofer, I. Marić and Y. El Shabrawi, "Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density", Cornea, vol. 41, no. 10, pp. 1255-1259, October 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:561005. [Accessed: 29 April 2024]

Metadata
Title (english)Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density
AuthorMarija Antičić-Eichwalder
AuthorSusanne Lex
AuthorStephanie Sarny
AuthorJakob Schweighofer
AuthorIvana Marić
AuthorYosuf El-Shabrawi
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Abstract (croatian)
Purpose:The purpose of this study was to compare the corneal endothelial morphology and cell density of diabetic smokers and nonsmokers with 50 to 70 age-matched healthy subjects and to determine whether smoking increases the effects of type 2 diabetes mellitus (DM) on these corneal parameters.Methods:This prospective cohort study included 200 patients who were assigned to 4 groups, including smokers with type 2 DM (group 1), nonsmokers with type 2 DM (group 2), healthy smokers (group 3), and healthy nonsmokers (control group, group 4). Noncontact specular microscopy was used to measure central endothelial cell density (ECD), coefficient of variation of cell area, percentage of hexagonal cells, and central corneal pachymetry (CCT).Results:According to the ECD and CCT values (P < 0.001 and P = 0.013, respectively), a significant difference was observed between the groups. The mean ECD was lowest in diabetic smokers (1917 ± 399 cells/mm2). Healthy smokers and diabetic smokers had significantly lower ECD compared with the control group (P = 0.03 and P < 0.001, respectively). Healthy smokers and diabetic smokers had significantly lower ECD compared with diabetic nonsmokers (P = 0.012 and P < 0.001, respectively). The cornea was significantly thicker in the diabetic smokers than in the control group (P = 0.013).Conclusions:The coexistence of DM and smoking causes a significant decrease in ECD and an increase in CCT. Cigarette smoking is more harmful to corneal endothelial cells than DM alone.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCornea
Numberingvol. 41, no. 10, pp. 1255-1259
p-ISSN0277-3740
DOIhttps://doi.org/10.1097/ICO.0000000000002917
URN:NBNurn:nbn:hr:184:561005
Publication2022-10
Document URLhttps://journals.lww.com/10.1097/ICO.0000000000002917
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-11-10 13:17:22