prikaz prve stranice dokumenta SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units
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Scientific paper - Original scientific paper
SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units
Scientific Reports, 12 (2022), 1; 14906. https://doi.org/10.1038/s41598-022-18991-2
Benes, Jan; Jankowski, Miłosz; Szułdrzynski, Konstanty; Zahorec, Roman; Lainscak, Mitja; Ruszkai, Zoltán; Podbregar, Matej; Zatloukal, Jan; Kletecka, Jakub; Kusza, Krzysztof; Szrama, Jakub; Ramic, Estera; Galkova, Katarina; Krbila, Stefan; Valky, Josef; Ivanic, Jaka; Kurnik, Marko; Mikó, Angéla; Kiss, Tamás; Hetényi, Barbara; Hegyi, Peter; Šustić, Alan; Molnar, Zsolt More authors...

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Benes, J., Jankowski, M., Szułdrzynski, K., Zahorec, R., Lainscak, M., Ruszkai, Z. ... Molnar, Z. (2022). SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units. Scientific Reports, 12. (1). doi: 10.1038/s41598-022-18991-2

Benes, Jan, et al. "SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units." Scientific Reports, vol. 12, no. 1, 2022. https://doi.org/10.1038/s41598-022-18991-2

Benes, Jan, Miłosz Jankowski, Konstanty Szułdrzynski, Roman Zahorec, Mitja Lainscak, Zoltán Ruszkai, Matej Podbregar, et al. "SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units." Scientific Reports 12, no. 1 (2022). https://doi.org/10.1038/s41598-022-18991-2

Benes, J., et al. (2022) 'SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units', Scientific Reports, 12(1). doi: 10.1038/s41598-022-18991-2

Benes J, Jankowski M, Szułdrzynski K, Zahorec R, Lainscak M, Ruszkai Z, and sur.. SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units. Scientific Reports [Internet]. 2022 September 01 [cited 2024 April 29];12(1). doi: 10.1038/s41598-022-18991-2

J. Benes, et al., "SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units", Scientific Reports, vol. 12, no. 1, September 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:730351. [Accessed: 29 April 2024]

Metadata
Title (english)SepsEast Registry indicates high mortality associated with COVID-19 caused acute respiratory failure in Central-Eastern European intensive care units
AuthorJan Benes
AuthorMiłosz Jankowski
AuthorKonstanty Szułdrzynski
AuthorRoman Zahorec
AuthorMitja Lainscak
AuthorZoltán Ruszkai
AuthorMatej Podbregar
AuthorJan Zatloukal
AuthorJakub Kletecka
AuthorKrzysztof Kusza
AuthorJakub Szrama
AuthorEstera Ramic
AuthorKatarina Galkova
AuthorStefan Krbila
AuthorJosef Valky
AuthorJaka Ivanic
AuthorMarko Kurnik
AuthorAngéla Mikó
AuthorTamás Kiss
AuthorBarbara Hetényi
AuthorPeter Hegyi
AuthorAlan Šustić
AuthorZsolt Molnar
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anaesthesiology,reanimatology and Intensive Care)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Abstract The coronavirus disease (COVID-19) pandemic caused unprecedented research activity all around the world but publications from Central-Eastern European countries remain scarce. Therefore, our aim was to characterise the features of the pandemic in the intensive care units (ICUs) among members of the SepsEast (Central-Eastern European Sepsis Forum) initiative. We conducted a retrospective, international, multicentre study between March 2020 and February 2021. All adult patients admitted to the ICU with pneumonia caused by COVID-19 were enrolled. Data on baseline and treatment characteristics, organ support and mortality were collected. Eleven centres from six countries provided data from 2139 patients. Patient characteristics were: median 68, [IQR 60–75] years of age; males: 67%; body mass index: 30.1 [27.0–34.7]; and 88% comorbidities. Overall mortality was 55%, which increased from 2020 to 2021 (p = 0.004). The major causes of death were respiratory (37%), cardiovascular (26%) and sepsis with multiorgan failure (21%). 1061 patients received invasive mechanical ventilation (mortality: 66%) without extracorporeal membrane oxygenation (n = 54). The rest of the patients received non-invasive ventilation (n = 129), high flow nasal oxygen (n = 317), conventional oxygen therapy (n = 122), as the highest level of ventilatory support, with mortality of 50%, 39% and 22%, respectively. This is the largest COVID-19 dataset from Central-Eastern European ICUs to date. The high mortality observed especially in those receiving invasive mechanical ventilation renders the need of establishing national–international ICU registries and audits in the region that could provide high quality, transparent data, not only during the pandemic, but also on a regular basis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleScientific Reports
Numberingvol. 12, no. 1, 14906
e-ISSN2045-2322
DOIhttps://doi.org/10.1038/s41598-022-18991-2
URN:NBNurn:nbn:hr:184:730351
Publication2022-09-01
Document URLhttps://www.nature.com/articles/s41598-022-18991-2
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-12-06 12:40:26