prikaz prve stranice dokumenta A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential
Access restricted to students and staff of home institution
Scientific paper - Original scientific paper
A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential
Clinical and Translational Imaging, 9 (2021), 5; 413-422. https://doi.org/10.1007/s40336-021-00439-8
Schenke, Simone Agnes; Campenni, Alfredo; Tuncel, Murat; Piccardo, Arnoldo; Sager, Sait; Bogović Crnčić, Tatjana; Rozić, Damir; Goerges, Rainer; Özcan Kara, Pinar Pelin; Groener, Daniel; Hautzel, Hubertus; Klett, Rigobert; Kreissl, Michael Christoph; Giovanella, Luca

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Schenke, S. A., Campenni, A., Tuncel, M., Piccardo, A., Sager, S., Bogović Crnčić, T. ... Giovanella, L. (2021). A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential. Clinical and Translational Imaging, 9. (5), 413-422. doi: 10.1007/s40336-021-00439-8

Schenke, Simone Agnes, et al. "A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential." Clinical and Translational Imaging, vol. 9, no. 5, 2021, pp. 413-422. https://doi.org/10.1007/s40336-021-00439-8

Schenke, Simone Agnes, Alfredo Campenni, Murat Tuncel, Arnoldo Piccardo, Sait Sager, Tatjana Bogović Crnčić, Damir Rozić, et al. "A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential." Clinical and Translational Imaging 9, no. 5 (2021): 413-422. https://doi.org/10.1007/s40336-021-00439-8

Schenke, S. A., et al. (2021) 'A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential', Clinical and Translational Imaging, 9(5), pp. 413-422. doi: 10.1007/s40336-021-00439-8

Schenke SA, Campenni A, Tuncel M, Piccardo A, Sager S, Bogović Crnčić T, and sur.. A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential. Clinical and Translational Imaging [Internet]. 2021 June 02 [cited 2024 December 26];9(5):413-422. doi: 10.1007/s40336-021-00439-8

S. A. Schenke, et al., "A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential", Clinical and Translational Imaging, vol. 9, no. 5, pp. 413-422, June 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:177639. [Accessed: 26 December 2024]

Metadata
Title (english)A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential
AuthorSimone Agnes Schenke
AuthorAlfredo Campenni
AuthorMurat Tuncel
AuthorArnoldo Piccardo
AuthorSait Sager
AuthorTatjana Bogović Crnčić
AuthorDamir Rozić
AuthorRainer Goerges
AuthorPinar Pelin Özcan Kara
AuthorDaniel Groener
AuthorHubertus Hautzel
AuthorRigobert Klett
AuthorMichael Christoph Kreissl
AuthorLuca Giovanella
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Nuclear Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Nuclear Medicine
Abstract (english)
Purpose Molecular imaging with 99mTc-methoxy-isobutyl- isonitrile (99mTc-MIBI, MIBI) has been used in the assessment of thyroid nodules (TNs) for more than two decades. Many studies showed that MIBI imaging is a suitable tool to rule-out malignancy when negative. However, relatively low specificity and accuracy have been described, thus, limiting its acceptance in clinical practice. Additionally, different technologies, protocols, and interpretation criteria are adopted accounting for heterogeneous data reported in the literature. Therefore, the present study was undertaken to assess the clinical use and methodology of MIBI imaging in patients with nodular thyroid disease in Europe. Methods A questionnaire was sent to 12 European centers of Nuclear Medicine. The questionnaire encompassed ultrasound (US) and fine-needle aspiration cytology (FNAC) procedures and their evaluation as well scintigraphy imaging indications, technical procedures, and interpretation criteria of MIBI imaging. Results The survey showed a good agreement of different centers in approaching TNs by TSH measurement, US evaluation and 99mTc-pertechnetate thyroid scintigraphy. MIBI imaging is mainly used to assess TNs with inconclusive/indeterminate cytological findings and selection of target nodule(s) for FNAC in patients with multi-nodular goiter. Technical procedures adopted in different centers are globally comparable and the recorded differences are unlikely to impact clinical results. However, as the main result of the present study, substantial differences were found in interpretation criteria adopted in different centers. Conclusions Our survey supports the urgent need of standardized interpretation criteria of thyroid MIBI imaging in order to improve its diagnostic performance and make results comparable in clinical practice
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleClinical and Translational Imaging
Numberingvol. 9, no. 5, pp. 413-422
p-ISSN2281-5872
e-ISSN2281-7565
DOIhttps://doi.org/10.1007/s40336-021-00439-8
URN:NBNurn:nbn:hr:184:177639
Publication2021-06-02
Document URLhttps://link.springer.com/10.1007/s40336-021-00439-8
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2023-02-01 08:39:20