prikaz prve stranice dokumenta Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm
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Scientific paper - Original scientific paper
Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm
International Journal of Molecular Sciences, 24 (2023), 8; 7249. https://doi.org/10.3390/ijms24087249
Begić, Gabrijela; Badovinac, Ivana Jelovica; Karleuša, Ljerka; Kralik, Kristina; Cvijanović Peloza, Olga; Kuiš, Davor; Gobin, Ivana

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Begić, G., Badovinac, I. J., Karleuša, Lj., Kralik, K., Cvijanović Peloza, O., Kuiš, D. & Gobin, I. (2023). Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm. International Journal of Molecular Sciences, 24. (8). doi: 10.3390/ijms24087249

Begić, Gabrijela, et al. "Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm." International Journal of Molecular Sciences, vol. 24, no. 8, 2023. https://doi.org/10.3390/ijms24087249

Begić, Gabrijela, Ivana Jelovica Badovinac, Ljerka Karleuša, Kristina Kralik, Olga Cvijanović Peloza, Davor Kuiš and Ivana Gobin. "Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm." International Journal of Molecular Sciences 24, no. 8 (2023). https://doi.org/10.3390/ijms24087249

Begić, G., et al. (2023) 'Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm', International Journal of Molecular Sciences, 24(8). doi: 10.3390/ijms24087249

Begić G, Badovinac IJ, Karleuša Lj, Kralik K, Cvijanović Peloza O, Kuiš D, and sur.. Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm. International Journal of Molecular Sciences [Internet]. 2023 April 14 [cited 2024 May 03];24(8). doi: 10.3390/ijms24087249

G. Begić, et al., "Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm", International Journal of Molecular Sciences, vol. 24, no. 8, April 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:415810. [Accessed: 03 May 2024]

Metadata
Title (english)Streptococcus salivarius as an Important Factor in Dental Biofilm Homeostasis: Influence on Streptococcus mutans and Aggregatibacter actinomycetemcomitans in Mixed Biofilm
AuthorGabrijela Begić
AuthorIvana Jelovica Badovinac
AuthorLjerka Karleuša
AuthorKristina Kralik
AuthorOlga Cvijanović Peloza
AuthorDavor Kuiš
AuthorIvana Gobin
Author's institution(Clinical Hospital Center Rijeka)
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
A disturbed balance within the dental biofilm can result in the dominance of cariogenic and periodontopathogenic species and disease development. Due to the failure of pharmacological treatment of biofilm infection, a preventive approach to promoting healthy oral microbiota is necessary. This study analyzed the influence of Streptococcus salivarius K12 on the development of a multispecies biofilm composed of Streptococcus mutans, S. oralis and Aggregatibacter actinomycetemcomitans. Four different materials were used: hydroxyapatite, dentin and two dense polytetrafluoroethylene (d-PTFE) membranes. Total bacteria, individual species and their proportions in the mixed biofilm were quantified. A qualitative analysis of the mixed biofilm was performed using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). The results showed that in the presence of S. salivarius K 12 in the initial stage of biofilm development, the proportion of S. mutans was reduced, which resulted in the inhibition of microcolony development and the complex three-dimensional structure of the biofilm. In the mature biofilm, a significantly lower proportion of the periodontopathogenic species A. actinomycetemcomitans was found in the salivarius biofilm. Our results show that S. salivarius K 12 can inhibit the growth of pathogens in the dental biofilm and help maintain the physiological balance in the oral microbiome.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 8, 7249
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24087249
URN:NBNurn:nbn:hr:184:415810
Publication2023-04-14
ProjectNumber: uniri-biomed-18-171
Title (croatian): Oportunistički patogeni vodoopskrbnog sustava: novi izazov u obradi voda
Title (english): Opportunistic Premise Plumbing Pathogens: New Challenge for Water Treatment
Leader: Ivana Gobin
Jurisdiction: Croatia
Funding stream: Nema
ProjectNumber: IP-2020-02-7875
Title (croatian): Usporedba reparacijskog odgovora koštanog tkiva upotrebom dentina, ksenogenog biomaterijala i autologne kosti
Acronym: MgXBiomBone
Leader: Olga Peloza
Jurisdiction: Croatia
Funding stream: IP
Document URLhttps://www.mdpi.com/1422-0067/24/8/7249
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-04-17 08:11:22