prikaz prve stranice dokumenta Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation
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Scientific paper - Original scientific paper
Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation
International Journal of Molecular Sciences, 24 (2023), 7; 6440. https://doi.org/10.3390/ijms24076440
Oguić, Matko; Čandrlić, Marija; Tomas, Matej; Vidaković, Bruno; Blašković, Marko; Jerbić Radetić, Ana Terezija; Zoričić Cvek, Sanja; Kuiš, Davor; Cvijanović Peloza, Olga

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Oguić, M., Čandrlić, M., Tomas, M., Vidaković, B., Blašković, M., Jerbić Radetić, A. T. ... Cvijanović Peloza, O. (2023). Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation. International Journal of Molecular Sciences, 24. (7). doi: 10.3390/ijms24076440

Oguić, Matko, et al. "Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation." International Journal of Molecular Sciences, vol. 24, no. 7, 2023. https://doi.org/10.3390/ijms24076440

Oguić, Matko, Marija Čandrlić, Matej Tomas, Bruno Vidaković, Marko Blašković, Ana Terezija Jerbić Radetić, Sanja Zoričić Cvek, Davor Kuiš and Olga Cvijanović Peloza. "Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation." International Journal of Molecular Sciences 24, no. 7 (2023). https://doi.org/10.3390/ijms24076440

Oguić, M., et al. (2023) 'Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation', International Journal of Molecular Sciences, 24(7). doi: 10.3390/ijms24076440

Oguić M, Čandrlić M, Tomas M, Vidaković B, Blašković M, Jerbić Radetić AT, and sur.. Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation. International Journal of Molecular Sciences [Internet]. 2023 March 29 [cited 2024 May 03];24(7). doi: 10.3390/ijms24076440

M. Oguić, et al., "Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation", International Journal of Molecular Sciences, vol. 24, no. 7, March 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:329892. [Accessed: 03 May 2024]

Metadata
Title (english)Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation
AuthorMatko Oguić
AuthorMarija Čandrlić
AuthorMatej Tomas
AuthorBruno Vidaković
AuthorMarko Blašković
AuthorAna Terezija Jerbić Radetić
AuthorSanja Zoričić Cvek
AuthorDavor Kuiš
AuthorOlga Cvijanović Peloza
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Anatomy
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
This prospective, randomized, controlled clinical trial reports clinical, radiographic, histologic and immunohistochemical results of autologous dentin graft (ADG) and its comparison with a mixture of bovine xenograft with autologous bone (BX+AB). After tooth extraction in the esthetic zone of maxilla, the alveolar ridge of 20 patients in the test group was augmented with ADG, while 17 patients in the control group received the combination of BX+AB. Cone beam computed tomography (CBCT) was performed before tooth extraction and after 4 months when a total of 22 bone biopsies were harvested and subjected to histological and immunohistochemical analysis. Radiological analysis showed comparable results of bone dimension loss in both groups. Quantitative histologic analysis showed comparable results with no statistically significant differences between the groups. Immunohistochemical staining with TNF-α and BMP-4 antibodies revealed immunopositivity in both groups. A statistically significant difference between the groups was found in the intensity of TNF-α in the area of newly formed bone (p = 0.0003) and around remaining biomaterial particles (p = 0.0027), and in the intensity of BMP-4 in the area around biomaterial particles (p = 0.0001). Overall, ADG showed biocompatibility and achieved successful bone regeneration in the esthetic zone of the maxilla similar to BX+AB.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 7, 6440
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24076440
URN:NBNurn:nbn:hr:184:329892
Publication2023-03-29
ProjectNumber: IP-2020-02-7875
Title (croatian): Usporedba reparacijskog odgovora koštanog tkiva upotrebom dentina, ksenogenog biomaterijala i autologne kosti
Acronym: MgXBiomBone
Leader: Olga Peloza
Jurisdiction: Croatia
Funding stream: IP
Document URLhttps://www.mdpi.com/1422-0067/24/7/6440
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-04-17 08:37:03