prikaz prve stranice dokumenta Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats
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Scientific paper - Original scientific paper
Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats
Croatica Chemica Acta, 68 (1995), 3; 485-490. urn:nbn:hr:184:107969
Župan, Gordana; Varljen, Jadranka; Eraković, Vesna; Mršić, Jasenka; Križ, Jasna; Simonić, Ante; Milin, Čedomila

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Župan, G., Varljen, J., Eraković, V., Mršić, J., Križ, J., Simonić, A. & Milin, Č. (1995). Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats. Croatica Chemica Acta, 68. (3), 485-490. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:107969

Župan, Gordana, et al. "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats." Croatica Chemica Acta, vol. 68, no. 3, 1995, pp. 485-490. https://urn.nsk.hr/urn:nbn:hr:184:107969

Župan, Gordana, Jadranka Varljen, Vesna Eraković, Jasenka Mršić, Jasna Križ, Ante Simonić and Čedomila Milin. "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats." Croatica Chemica Acta 68, no. 3 (1995): 485-490. https://urn.nsk.hr/urn:nbn:hr:184:107969

Župan, G., et al. (1995) 'Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats', Croatica Chemica Acta, 68(3), pp. 485-490. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969 (Accessed 06 May 2024)

Župan G, Varljen J, Eraković V, Mršić J, Križ J, Simonić A, and sur.. Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats. Croatica Chemica Acta [Internet]. 1995 [cited 2024 May 06];68(3):485-490. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969

G. Župan, et al., "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats", Croatica Chemica Acta, vol. 68, no. 3, pp. 485-490, 1995. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969. [Accessed: 06 May 2024]

Metadata
Title (english)Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats
AuthorGordana Župan
AuthorJadranka Varljen
AuthorVesna Eraković
AuthorJasenka Mršić
AuthorJasna Križ
AuthorAnte Simonić
AuthorČedomila Milin
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pharmacology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Medical Biochemistry
Abstract (english)
The aim of this study was to determine the dynamics of the brain free fatty acid (FFA) pool in rats exposed to: (a) controlled hypoxia, and (b) experimental epilepsy. Animals from group (a) were subjected to hypoxia procedure. Immediately, 5,15 or 60 minutes after losing the righting reflex, the animals were decapitated and brains were quickly removed. Animals from group (b) received penicillin (5000 U/5 pi) into the left lateral ventricle and were decapitated immediately, 5 or 15 minutes after the appearance of epileptic seizures. The FFA were quantified by gas chromatography. An increase in the total brain FFA content with the maximum level at 60 minutes after losing the righting reflex was detected in hypoxia- exposed rats. The highest level of the brain free arachidonic acid (FAA) was detected 15 minutes after hypoxia. Seizures also produced an increase in the total brain FFA and brain FAA, with a statistically significant level 5 minutes after the appearance of epileptic seizures.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 68, no. 3, pp. 485-490
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:184:107969
Publication1995
Document URLhttps://hrcak.srce.hr/136709
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-04-21 07:57:22