prikaz prve stranice dokumenta Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats
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Scientific paper - Original scientific paper
Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats
Biological Trace Element Research, 143 (2010), 1; 332-343. https://doi.org/10.1007/s12011-010-8841-8
Tota, Marin; Jakovac, Hrvoje; Grebić, Damir; Marinić, Jelena; Broznić, Dalibor; Čanadi Jurešić, Gordana; Milin, Čedomila; Radošević-Stašić, Biserka

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Tota, M., Jakovac, H., Grebić, D., Marinić, J., Broznić, D., Čanadi Jurešić, G. ... Radošević Stašić, B. (2010). Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats. Biological Trace Element Research, 143. (1), 332-343. doi: 10.1007/s12011-010-8841-8

Tota, Marin, et al. "Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats." Biological Trace Element Research, vol. 143, no. 1, 2010, pp. 332-343. https://doi.org/10.1007/s12011-010-8841-8

Tota, Marin, Hrvoje Jakovac, Damir Grebić, Jelena Marinić, Dalibor Broznić, Gordana Čanadi Jurešić, Čedomila Milin and Biserka Radošević Stašić. "Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats." Biological Trace Element Research 143, no. 1 (2010): 332-343. https://doi.org/10.1007/s12011-010-8841-8

Tota, M., et al. (2010) 'Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats', Biological Trace Element Research, 143(1), pp. 332-343. doi: 10.1007/s12011-010-8841-8

Tota M, Jakovac H, Grebić D, Marinić J, Broznić D, Čanadi Jurešić G, and sur.. Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats. Biological Trace Element Research [Internet]. 2010 September 16 [cited 2024 October 03];143(1):332-343. doi: 10.1007/s12011-010-8841-8

M. Tota, et al., "Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats", Biological Trace Element Research, vol. 143, no. 1, pp. 332-343, September 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:680153. [Accessed: 03 October 2024]

Metadata
Title (english)Kinetics of Tissue Iron in Experimental Autoimmune Encephalomyelitis in Rats
AuthorMarin Tota
AuthorHrvoje Jakovac
AuthorDamir Grebić
AuthorJelena Marinić
AuthorDalibor Broznić
AuthorGordana Čanadi Jurešić
AuthorČedomila Milin
AuthorBiserka Radošević-Stašić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Surgery)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
To elucidate the role of iron in the pathomechanisms of autoimmune CNS disorders, we estimated the tissue concentrations of Fe2+ in the brain, spinal cord, and liver in the chronic relapsing form of experimental autoimmune encephalomyelitis (EAE). The disease was induced in Dark Agouti (DA) strain of rats, by subcutaneous injection of bovine brain homogenate in complete Freund's adjuvant (CFA). Control rats consisted of unsensitized rats and of rats treated with CFA or saline. The data obtained by clinical assessment and by inductively coupled plasma spectrometry have shown that the attacks of disease (on the 12th and 22nd post-immunization day) were followed by high accumulation of iron in the liver. Additionally, during the second attack of disease, the decreased concentration of Fe2+ was found in cervical spinal cord. The data point to regulatory effects of iron and hepatic trace elements regulating mechanisms in the pathogenesis of EAE
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiological Trace Element Research
Numberingvol. 143, no. 1, pp. 332-343
p-ISSN0163-4984
e-ISSN1559-0720
DOIhttps://doi.org/10.1007/s12011-010-8841-8
URN:NBNurn:nbn:hr:184:680153
Publication2010-09-16
ProjectNumber: 062-0621341-0061
Title (croatian): Masne kiseline i polifenoli u regeneraciji i reparaciji tkiva.
Title (english): Fatty acids and polyphenols in tissue regeneration and reparation.
Leader: Čedomila Milin
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://link.springer.com/10.1007/s12011-010-8841-8
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2023-05-02 08:00:17