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Scientific paper - Case study
Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report
Journal of Medical Case Reports, 3 (2009), 1; 7270. https://doi.org/10.1186/1752-1947-3-7270
Turk, Tamara; Crnčević Orlić, Željka; Smoljan, Ivana; Načinović, Antica; Bekafigo, Irena Seili; Radić, Jelena; Zamolo, Gordana

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Turk, T., Crnčević Orlić, Ž., Smoljan, I., Načinović, A., Bekafigo, I. S., Radić, J. & Zamolo, G. (2009). Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report. Journal of Medical Case Reports, 3. (1). doi: 10.1186/1752-1947-3-7270

Turk, Tamara, et al. "Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report." Journal of Medical Case Reports, vol. 3, no. 1, 2009. https://doi.org/10.1186/1752-1947-3-7270

Turk, Tamara, Željka Crnčević Orlić, Ivana Smoljan, Antica Načinović, Irena Seili Bekafigo, Jelena Radić and Gordana Zamolo. "Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report." Journal of Medical Case Reports 3, no. 1 (2009). https://doi.org/10.1186/1752-1947-3-7270

Turk, T., et al. (2009) 'Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report', Journal of Medical Case Reports, 3(1). doi: 10.1186/1752-1947-3-7270

Turk T, Crnčević Orlić Ž, Smoljan I, Načinović A, Bekafigo IS, Radić J, and sur.. Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report. Journal of Medical Case Reports [Internet]. 2009 May 27 [cited 2024 April 28];3(1). doi: 10.1186/1752-1947-3-7270

T. Turk, et al., "Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report", Journal of Medical Case Reports, vol. 3, no. 1, May 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:685071. [Accessed: 28 April 2024]

Metadata
Title (english)Spontaneous regression of Merkel cell carcinoma in a patient with chronic lymphocytic leukemia: a case report
AuthorTamara Turk
AuthorŽeljka Crnčević Orlić
AuthorIvana Smoljan
AuthorAntica Načinović
AuthorIrena Seili Bekafigo
AuthorJelena Radić
AuthorGordana Zamolo
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Introduction: Merkel cell carcinoma is a rare and aggressive primary cutaneous neuroendocrine malignant tumor. The tumor has a high rate of local recurrence after surgical removal. Spontaneous regression appears to be relatively common in this rare type of tumor. Case presentation: We describe the clinical course, cytological and histological findings of a Merkel cell carcinoma in a 70-year-old Caucasian woman, simultaneously diagnosed with chronic lymphatic leukemia. The tumor showed clinical regression after fine needle aspiration. At primary presentation, the tumor had no apparent leukocyte infiltration, but was completely cleared by T-cell mediated immunity within 3 weeks after fine needle aspiration. Conclusion: Fine needle aspiration may have acted as a mechanical trigger involved in the activation of cell-mediated immunity, leading to the clinical and histological regression of the tumor. To the best of our knowledge, this is the first case report of spontaneous regression of Merkel cell carcinoma in a patient with a co-malignancy, that is to say, chronic lymphocytic leukemia
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Medical Case Reports
Numberingvol. 3, no. 1, 7270
e-ISSN1752-1947
DOIhttps://doi.org/10.1186/1752-1947-3-7270
URN:NBNurn:nbn:hr:184:685071
Publication2009-05-27
Document URLhttps://jmedicalcasereports.biomedcentral.com/articles/10.1186/1752-1947-3-7270
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-05-15 12:47:31