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master's thesis
Novosti u terapiji karcinoma dojke
diplomski rad
Rijeka: University of Rijeka, Faculty of Medicine, 2023. urn:nbn:hr:184:432024
Čubranić, Antonia
University of Rijeka
Faculty of Medicine
Department of Pharmacology

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Čubranić, A. (2023). Novosti u terapiji karcinoma dojke : diplomski rad (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:432024

Čubranić, Antonia. "Novosti u terapiji karcinoma dojke : diplomski rad." Master's thesis, University of Rijeka, Faculty of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:184:432024

Čubranić, Antonia. "Novosti u terapiji karcinoma dojke : diplomski rad." Master's thesis, University of Rijeka, Faculty of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:184:432024

Čubranić, A. (2023). 'Novosti u terapiji karcinoma dojke : diplomski rad', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:432024

Čubranić A. Novosti u terapiji karcinoma dojke : diplomski rad [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2023 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:184:432024

A. Čubranić, "Novosti u terapiji karcinoma dojke : diplomski rad", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:184:432024

Metadata
TitleNovosti u terapiji karcinoma dojke : diplomski rad
Title (english)Novelties of breast cancer therapy
AuthorAntonia Čubranić
MentorJasenka Mršić-Pelčić (mentor)
Committee memberDinko Vitezić (predsjednik povjerenstva)
Committee memberKristina Pilipović (član povjerenstva)
Committee memberPetra Dolenec (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Pharmacology)
Rijeka
Defense date and country2023-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract
Karcinom dojke je najčešće dijagnosticirani karcinom ženske populacije. Terapija karcinoma dojke posljednjih je godina doživjela značajni napredak, a noviteti nude dodatne mogućnosti i poboljšane ishode za svakog pojedinca pogođenog ovom bolešću. Među najznačajnije napretke u liječenju svrstava se razvoj ciljanih terapija i imunoterapije. Nadalje, genomsko profiliranje otvorilo je vrata preciznoj medicini koja se temelji na specifičnoj prilagodbi svakom pojedinom pacijentu. Ispitivanja o utjecaju genetike na razvoj terapijske rezistencije mogla bi pridonijeti razvoju personaliziranih lijekova s djelovanjem na temelju polimorfizma gena. Upotrebom nanočestica postiže se ciljano djelovanje lijeka na tumorske stanice, ali istodobno i dijagnostička korist. Konačno, posljednjih godina razvila se neinvazivna metoda analize tumorskih biomarkera koja omogućava jednostavno praćenje bolesti i adekvatnu prilagodbu plana liječenja. Budući ciljevi su prilagodba inovacija za svakodnevnu kliničku primjenu te velik broj novih ispitivanja čijim bi se spoznajama moglo približiti pobjedi nad karcinomom dojke.
Abstract (english)
Breast cancer is the most commonly diagnosed cancer in the female population. Breast cancer therapy has made significant advancements in recent years, and these novelties offer additional possibilities and improved outcomes for individuals affected by this disease. Among the most significant advances in treatment are the development of targeted therapies and immunotherapy. Furthermore, genomic profiling has opened the doors to precision medicine, which is based on specific adaptations for each individual patient. Studies on the impact of genetics on the development of therapeutic resistance could contribute to the evolution of personalized drugs based on gene polymorphism. The use of nanoparticles enables targeted drug action on tumor cells while also providing diagnostic benefit. Finally, in recent years, non-invasive methods for analyzing tumor biomarkers have been developed, allowing for easy disease monitoring and appropriate adjustment of the treatment plan. The future goals are the adaptation of innovations for everyday clinical use and a large number of new studies that could bring us closer to defeating breast cancer.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:432024
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-06-30 18:20:17