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Scientific paper - Review paper
Nanoparticles in Medicine: Current Status in Cancer Treatment
International Journal of Molecular Sciences, 24 (2023), 16; 12827. https://doi.org/10.3390/ijms241612827
Pavelić, Krešimir; Kraljević Pavelić, Sandra Kraljević; Bulog, Aleksandar; Agaj, Andrea; Rojnić, Barbara; Čolić, Miroslav; Trivanović, Dragan

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Pavelić, K., Kraljević Pavelić, S. K., Bulog, A., Agaj, A., Rojnić, B., Čolić, M. & Trivanović, D. (2023). Nanoparticles in Medicine: Current Status in Cancer Treatment. International Journal of Molecular Sciences, 24. (16). doi: 10.3390/ijms241612827

Pavelić, Krešimir, et al. "Nanoparticles in Medicine: Current Status in Cancer Treatment." International Journal of Molecular Sciences, vol. 24, no. 16, 2023. https://doi.org/10.3390/ijms241612827

Pavelić, Krešimir, Sandra Kraljević Kraljević Pavelić, Aleksandar Bulog, Andrea Agaj, Barbara Rojnić, Miroslav Čolić and Dragan Trivanović. "Nanoparticles in Medicine: Current Status in Cancer Treatment." International Journal of Molecular Sciences 24, no. 16 (2023). https://doi.org/10.3390/ijms241612827

Pavelić, K., et al. (2023) 'Nanoparticles in Medicine: Current Status in Cancer Treatment', International Journal of Molecular Sciences, 24(16). doi: 10.3390/ijms241612827

Pavelić K, Kraljević Pavelić SK, Bulog A, Agaj A, Rojnić B, Čolić M, and sur.. Nanoparticles in Medicine: Current Status in Cancer Treatment. International Journal of Molecular Sciences [Internet]. 2023 August 15 [cited 2024 May 17];24(16). doi: 10.3390/ijms241612827

K. Pavelić, et al., "Nanoparticles in Medicine: Current Status in Cancer Treatment", International Journal of Molecular Sciences, vol. 24, no. 16, August 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:456910. [Accessed: 17 May 2024]

Metadata
Title (english)Nanoparticles in Medicine: Current Status in Cancer Treatment
AuthorKrešimir Pavelić
AuthorSandra Kraljević Kraljević Pavelić
AuthorAleksandar Bulog
AuthorAndrea Agaj
AuthorBarbara Rojnić
AuthorMiroslav Čolić
AuthorDragan Trivanović
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		INTERDISCIPLINARY AREAS OF KNOWLEDGE
Biotechnology in Biomedicine (natural science, biomedicine and healthcare, bioethics area
Abstract (english)
Cancer is still a leading cause of deaths worldwide, especially due to those cases diagnosed at late stages with metastases that are still considered untreatable and are managed in such a way that a lengthy chronic state is achieved. Nanotechnology has been acknowledged as one possible solution to improve existing cancer treatments, but also as an innovative approach to developing new therapeutic solutions that will lower systemic toxicity and increase targeted action on tumors and metastatic tumor cells. In particular, the nanoparticles studied in the context of cancer treatment include organic and inorganic particles whose role may often be expanded into diagnostic applications. Some of the best studied nanoparticles include metallic gold and silver nanoparticles, quantum dots, polymeric nanoparticles, carbon nanotubes and graphene, with diverse mechanisms of action such as, for example, the increased induction of reactive oxygen species, increased cellular uptake and functionalization properties for improved targeted delivery. Recently, novel nanoparticles for improved cancer cell targeting also include nanobubbles, which have already demonstrated increased localization of anticancer molecules in tumor tissues. In this review, we will accordingly present and discuss state-of-the-art nanoparticles and nano-formulations for cancer treatment and limitations for their application in a clinical setting.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 16, 12827
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms241612827
URN:NBNurn:nbn:hr:184:456910
Publication2023-08-15
Document URLhttps://www.mdpi.com/1422-0067/24/16/12827
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-08-17 10:24:28