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Scientific paper - Original scientific paper
The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study
Journal of Clinical Medicine, 12 (2023), 22; 7158. https://doi.org/10.3390/jcm12227158
Bedeković, Dražen; Kirner, Damir; Bošnjak, Ivica; Kibel, Aleksandar; Šarić, Sandra; Novak, Srđan; Prus, Višnja

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Bedeković, D., Kirner, D., Bošnjak, I., Kibel, A., Šarić, S., Novak, S. & Prus, V. (2023). The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study. Journal of Clinical Medicine, 12. (22). doi: 10.3390/jcm12227158

Bedeković, Dražen, et al. "The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study." Journal of Clinical Medicine, vol. 12, no. 22, 2023. https://doi.org/10.3390/jcm12227158

Bedeković, Dražen, Damir Kirner, Ivica Bošnjak, Aleksandar Kibel, Sandra Šarić, Srđan Novak and Višnja Prus. "The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study." Journal of Clinical Medicine 12, no. 22 (2023). https://doi.org/10.3390/jcm12227158

Bedeković, D., et al. (2023) 'The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study', Journal of Clinical Medicine, 12(22). doi: 10.3390/jcm12227158

Bedeković D, Kirner D, Bošnjak I, Kibel A, Šarić S, Novak S, and sur.. The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study. Journal of Clinical Medicine [Internet]. 2023 November 18 [cited 2024 May 13];12(22). doi: 10.3390/jcm12227158

D. Bedeković, et al., "The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study", Journal of Clinical Medicine, vol. 12, no. 22, November 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:258168. [Accessed: 13 May 2024]

Metadata
Title (english)The Influence of Rheumatoid Arthritis and Osteoarthritis on the Occurrence of Arterial Hypertension: An 8-Year Prospective Clinical Observational Cohort Study
AuthorDražen Bedeković
AuthorDamir Kirner
AuthorIvica Bošnjak
AuthorAleksandar Kibel
AuthorSandra Šarić
AuthorSrđan Novak
AuthorVišnja Prus
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Rheumatoid arthritis (RA) increases the risk of cardiovascular mortality and morbidity, including a 50–60% increased risk of cardiovascular disease (CVD). Arterial hypertension (HT) is considered the major contributing risk factor for CVD development in RA patients. In this investigation, we compared the incidence and prevalence of HT between RA and osteoarthritis (OA) and the influence of HT on CVD development in CVD-naive patients in both groups. This was a prospective clinical cohort investigation with an 8-year follow-up period. A total of 201 participants, 124 with RA (investigation group) and 77 with OA (control group), without diagnosed CVD or symptomatic heart failure were included. After selection according to inclusion and exclusion criteria, both groups underwent initial and final visits, and the investigation group underwent annual visits to assess disease activity. Case report forms were completed for each visit. The obtained data were analyzed by a statistician. No difference in the incidence or prevalence of HT was found between the investigation and control groups. No difference in the prevalence of HT was reported between the study groups and age-standardized data from the general population. The investigation group had a higher incidence of CVD than the control group. RA participants with long-term remission had a marginally lower HT prevalence. Although previous studies reported a higher HT prevalence in RA than in OA and the general population, our findings did not support this. The RA group had a higher incidence of CVD, but it is possible that optimal disease control with long-term remission could reduce HT incidence and prevalence while also having beneficial effects on other cardiovascular risk factors (CV) and, consequently, CVD occurrence.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 12, no. 22, 7158
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm12227158
URN:NBNurn:nbn:hr:184:258168
Publication2023-11-18
Document URLhttps://www.mdpi.com/2077-0383/12/22/7158
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-11-30 07:55:26