Bladder cancer is a malignant neoplasm arising usually from the transitional epithelium. It's four times more common in men than in women. It is also twice as common in Caucasians compared to blacks. The average age of patients with the mentioned disease is 73 years. According to data from the Croatian Institute of Public Health for the year 2021, bladder cancer is the fourth most common cancer in men in the Republic of Croatia with a total of 836 cases that year. Etiological factors are most often environmental: cigarette smoking, professional environment with aniline dyes, HPV infection, Schistosoma infestation, urinary stones, drugs such as cyclophosphamide, etc. In a smaller percentage, there is genetically caused bladder cancer, most often provoked by environmental factors. It is diagnosed with a good medical history, physical status with included ultrasound, and the gold standard is cystoscopy. The transurethral resection is performed in all patients. It is also the method of choice in certain cases. Treatment is carried out by surgery, radiotherapy, chemotherapy and immunotherapy. The choice of means of treatment depends on the TNM classification, the general condition of the patient and the pathohistological findings.