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master's thesis
Uzročni čimbenici pojave epidemije hripavca
Rijeka: University of Rijeka, Faculty of Medicine, 2024. urn:nbn:hr:184:002107
Vojnić, Matea
University of Rijeka
Faculty of Medicine

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Vojnić, M. (2024). Uzročni čimbenici pojave epidemije hripavca (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:002107

Vojnić, Matea. "Uzročni čimbenici pojave epidemije hripavca." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:002107

Vojnić, Matea. "Uzročni čimbenici pojave epidemije hripavca." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:002107

Vojnić, M. (2024). 'Uzročni čimbenici pojave epidemije hripavca', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 25 December 2024, https://urn.nsk.hr/urn:nbn:hr:184:002107

Vojnić M. Uzročni čimbenici pojave epidemije hripavca [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 December 25] Available at: https://urn.nsk.hr/urn:nbn:hr:184:002107

M. Vojnić, "Uzročni čimbenici pojave epidemije hripavca", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:002107

Metadata
TitleUzročni čimbenici pojave epidemije hripavca
Title (english)Causal factors of the pertussis epidemic
AuthorMatea Vojnić
MentorSrđan Banac (mentor)
Committee memberKristina Lah Tomulić (predsjednik povjerenstva)
Committee memberMorana Tomljenović (član povjerenstva)
Committee memberIvica Pavić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
Rijeka
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Hripavac je akutna zarazna bolest uzrokovana bakterijom Bordetella pertussis čija su glavna karakteristika napadaji spazmatičnog kašlja koji završavaju forsiranim inspirijem, a ponekad i povraćanjem. Od hripavca najčešće obolijevaju mala djeca. U doba prije uvođenja antibiotske terapije i cjepiva, hripavac je uzrokovao veću smrtnost male djece nego bilo koja druga akutna zarazna bolest. Postoje cjelostanična i acelularna cjepiva protiv hripavca koja se razlikuju po reaktogenosti i imunogenosti, no oba cjepiva su se pokazala učinkovitim u suzbijanju broja oboljelih od hripavca. Nedavni porasti broja slučajeva postavljaju pitanje o sposobnosti acelularnog cjepiva da optimalno podrži dugoročnu zaštitu. Oba su cjepiva sigurna i štite populaciju od hripavca. Slabija učinkovitost cjepiva tijekom vremena, niska procijepljenost ili nepravovremeno cijepljenje uvelike pridonose pojavama epidemija. Za kontrolu hripavca i zaštitu osjetljivih skupina ključna je visoka procijepljenost protiv uzročnika koja značajno smanjuje broj slučajeva i izbijanje epidemija.
Abstract (english)
Whooping cough is an acute infectious disease caused by the bacterium Bordetella pertussis, characterized by episodes of spasmodic coughing that end with forced inhalation, and sometimes vomiting. It most commonly affects young children. Before the introduction of antibiotic therapy and vaccines, pertussis caused higher mortality in young children than any other acute infectious disease. There are whole-cell and acellular vaccines against pertussis, which differ in reactogenicity and immunogenicity, but both have proven effective in reducing the number of cases. Recent increases in cases raise questions about the ability of the acellular vaccine to optimally support long-term protection. Both vaccines are safe and protect the population against pertussis. Lower vaccine effectiveness over time, low vaccination coverage, or untimely vaccination greatly contribute to outbreaks. High vaccination coverage is key to controlling pertussis and protecting vulnerable groups, significantly reducing the number of cases and outbreaks.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:002107
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-06-28 11:14:09