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Scientific paper - Case study
Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja
Medicina Fluminensis : Medicina Fluminensis, 44 (2008), 3-4; 313-318. urn:nbn:hr:184:886536
Guina, Tina; Kaštelan, Marija; Brajac, Ines

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Guina, T., Kaštelan, M. & Brajac, I. (2008). Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja. Medicina Fluminensis : Medicina Fluminensis, 44. (3-4), 313-318. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:886536

Guina, Tina, et al. "Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja." Medicina Fluminensis : Medicina Fluminensis, vol. 44, no. 3-4, 2008, pp. 313-318. https://urn.nsk.hr/urn:nbn:hr:184:886536

Guina, Tina, Marija Kaštelan and Ines Brajac. "Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja." Medicina Fluminensis : Medicina Fluminensis 44, no. 3-4 (2008): 313-318. https://urn.nsk.hr/urn:nbn:hr:184:886536

Guina, T., Kaštelan, M. and Brajac, I. (2008) 'Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja', Medicina Fluminensis : Medicina Fluminensis, 44(3-4), pp. 313-318. Available at: https://urn.nsk.hr/urn:nbn:hr:184:886536 (Accessed 10 May 2024)

Guina T, Kaštelan M, Brajac I. Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2008 December 01 [cited 2024 May 10];44(3-4):313-318. Available at: https://urn.nsk.hr/urn:nbn:hr:184:886536

T. Guina, M. Kaštelan and I. Brajac, "Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja", Medicina Fluminensis : Medicina Fluminensis, vol. 44, no. 3-4, pp. 313-318, December 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:886536. [Accessed: 10 May 2024]

Metadata
Title (croatian)Primjena fototerapije u bolesnika s generaliziranim vitiligom – prikaz slučaja
Title (english)Phototherapy in the treatment of generalized vitiligo – a case report
AuthorTina Guina
AuthorMarija Kaštelan
AuthorInes Brajac
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract (croatian)
Cilj: Cilj rada je prikaz slučaja bolesnika s generaliziranim oblikom vitiliga koji je liječen lokalnim kortikosteroidima i uskospektralnom UVB fototerapijom, kao i pregled novih oblika liječenja vitiliga. Prikaz slučaja: Četrdesetdvogodišnji bolesnik zaprimljen je zbog generalizirane pojave vitiliga. Kliničkim pregledom uočene su depigmentirane mliječnobijele makule simetrično raspoređene po koži lateralnih strana trupa, gornjih i donjih ekstremiteta, kao i vratu te periorbitalno na desnoj strani lica. U terapiju je uvedena kortikosteroidna krema, mometazon furoat, a potom i uskospektralna UVB fototerapija koja se provodila tri puta tjedno uz povećanje doze za 20% prilikom svakog obasjavanja do pojave blagog eritema. Ukupna primljena doza iznosila je 69.213 J/cm2. Liječenje je dovelo do poboljšanja u smislu mjestimične repigmentacije vitiliginoznih lezija, zaustavljena je progresija postojećih, kao i nastajanje novih lezija. Rasprava i zaključak: Iako postoje brojne dostupne metode liječenja, ne postoji univerzalna terapija koja bi bila učinkovita u svih bolesnika s vitiligom. Raznolikost kliničke slike vitiliga posljedica je različitih patogenetskih mehanizama, stoga zahtijeva i različite pristupe u liječenju. Nova istraživanja na polju etiopatogeneze vitiliga omogućit će razvoj novih učinkovitijih modaliteta liječenja koji bi doveli do trajnog izlječenja bolesti.
Abstract (english)
Aim: To present a patient with generalized vitiligo who was treated with topical corticosteroids and narrow band ultraviolet B phototherapy and to give an overview of treatment modalities for vitiligo. Case report: A 42 year-old men was admitted because of generalized vitiligo. Clinical examination revealed depigmented milky-white macules distributed symmetrically on lateral sides of trunk, upper and lower extremities, neck and periorbital region of the right facial side. A topical corticosteroid, mometazon furoat, was prescribed once a day and narrow band UVB phototherapy was initiated. Phototherapy was administered three times a week with the initial dose of 0.3 J/cm2 and dose increment at the rate of 20% of the previous dose until the formation of a mild erythema. Total dose received was 69.213 J/cm2. After received therapy, repigmentation was partially achieved, and the progression, as well as the appearance of the new vitiliginous lesions, were stopped. Discussion and conclusion: Various modalities of treatment are used in therapy of vitiligo, but there is still no universal therapy that could be effective in all vitiligo patients. Different clinical manifestations of vitiligo are the result of different pathogenetic mechanisms and require different treatment approaches. Therefore, future research is needed in order to clarify the etiopathogenetic mechanisms and provide new, more effective therapeutic opportunities
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 44, no. 3-4, pp. 313-318
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:886536
Publication2008-12-01
Document URLhttp://hrcak.srce.hr/31404
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-05-02 13:26:20