Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes

Kršek, Antea; Batičić, Lara; Sotošek, Vlatka

doi:10.3390/cardiogenetics14030012

prikaz prve stranice dokumenta Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes

Scientific paper - Review paper

Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes

Cardiogenetics, 14 (2024), 3; 149-169. https://doi.org/10.3390/cardiogenetics14030012

Kršek, Antea; Batičić, Lara; Sotošek, Vlatka

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

APA 6th Edition

Kršek, A., Batičić, L. & Sotošek, V. (2024). Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes. Cardiogenetics, 14. (3), 149-169. doi: 10.3390/cardiogenetics14030012

MLA 8th Edition

Kršek, Antea, et al. "Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes." Cardiogenetics, vol. 14, no. 3, 2024, pp. 149-169. https://doi.org/10.3390/cardiogenetics14030012

Chicago 17th Edition

Kršek, Antea, Lara Batičić and Vlatka Sotošek. "Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes." Cardiogenetics 14, no. 3 (2024): 149-169. https://doi.org/10.3390/cardiogenetics14030012

Harvard

Kršek, A., Batičić, L. and Sotošek, V. (2024) 'Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes', Cardiogenetics, 14(3), pp. 149-169. doi: 10.3390/cardiogenetics14030012

Vancouver

Kršek A, Batičić L, Sotošek V. Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes. Cardiogenetics [Internet]. 2024 September 02 [cited 2024 November 09];14(3):149-169. doi: 10.3390/cardiogenetics14030012

IEEE

A. Kršek, L. Batičić and V. Sotošek, "Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes", Cardiogenetics, vol. 14, no. 3, pp. 149-169, September 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:793755. [Accessed: 09 November 2024]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:184:793755

Metadata

Title (english)	Beyond the Beat: Understanding Inherited Risk and Therapeutic Opportunities in Cardiovascular Diseases with Emphasis on Inherited Cardiomyopathies and Inherited Arrhythmic Syndromes
Author	Antea Kršek
Author	Lara Batičić
Author	Vlatka Sotošek
Author's institution	University of Rijeka Faculty of Medicine (Department of Anaesthesiology,reanimatology and Intensive Care)
Author's institution	University of Rijeka Faculty of Medicine (Department of Chemistry and Biochemistry)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Internal Medicine
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Basic Medical Sciences
Abstract (english)	Over the past three decades, significant progress has been made in elucidating the intricate connection between genetic predispositions and cardiovascular diseases (CVDs). Through extensive investigation, numerous genetic variants linked to various cardiovascular conditions have been discovered, shedding crucial light on the underlying biological mechanisms and pathways. These discoveries have not only revolutionized risk assessment for patients but have also paved the way for personalized treatment strategies, allowing healthcare providers to tailor interventions according to individual genetic profiles. Furthermore, genetic testing has facilitated cascade screening, enabling the early identification and intervention of potential cardiovascular issues among at-risk biological family members. This review aims to comprehensively summarize the current state of knowledge regarding inherited risk and novel insights from human genome and epigenome research, as well as therapeutic opportunities in CVDs with special emphasis on inherited cardiomyopathies and inherited arrhythmic syndromes. The newest translational trials for CVDs and pharmaceutical approaches are discussed, including gene therapy options for heart failure and cardiomyopathies.
Keywords (english)
Language	english
Publication type	Scientific paper - Review paper
Publication status	Published
Peer review	Peer review - international
Publication version	Published version
Journal title	Cardiogenetics
Numbering	vol. 14, no. 3, pp. 149-169
e-ISSN	2035-8148
DOI	https://doi.org/10.3390/cardiogenetics14030012
URN:NBN	urn:nbn:hr:184:793755
Publication	2024-09-02
Document URL	https://www.mdpi.com/2035-8148/14/3/12
Type of resource	Text
Access conditions	Open access
Terms of use
Created on	2024-09-05 10:16:24

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