prikaz prve stranice dokumenta Immune surveillance of cytomegalovirus in tissues
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Scientific paper - Review paper
Immune surveillance of cytomegalovirus in tissues
Cellular & Molecular Immunology, 21 (2024), 9; 959-981. https://doi.org/10.1038/s41423-024-01186-2
Mihalić, Andrea; Železnjak, Jelena; Lisnić, Berislav; Jonjić, Stipan; Juranić Lisnić, Vanda; Brizić, Ilija

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Mihalić, A., Železnjak, J., Lisnić, B., Jonjić, S., Juranić Lisnić, V. & Brizić, I. (2024). Immune surveillance of cytomegalovirus in tissues. Cellular & Molecular Immunology, 21. (9), 959-981. doi: 10.1038/s41423-024-01186-2

Mihalić, Andrea, et al. "Immune surveillance of cytomegalovirus in tissues." Cellular & Molecular Immunology, vol. 21, no. 9, 2024, pp. 959-981. https://doi.org/10.1038/s41423-024-01186-2

Mihalić, Andrea, Jelena Železnjak, Berislav Lisnić, Stipan Jonjić, Vanda Juranić Lisnić and Ilija Brizić. "Immune surveillance of cytomegalovirus in tissues." Cellular & Molecular Immunology 21, no. 9 (2024): 959-981. https://doi.org/10.1038/s41423-024-01186-2

Mihalić, A., et al. (2024) 'Immune surveillance of cytomegalovirus in tissues', Cellular & Molecular Immunology, 21(9), pp. 959-981. doi: 10.1038/s41423-024-01186-2

Mihalić A, Železnjak J, Lisnić B, Jonjić S, Juranić Lisnić V, Brizić I. Immune surveillance of cytomegalovirus in tissues. Cellular & Molecular Immunology [Internet]. 2024 August 12 [cited 2024 October 05];21(9):959-981. doi: 10.1038/s41423-024-01186-2

A. Mihalić, J. Železnjak, B. Lisnić, S. Jonjić, V. Juranić Lisnić and I. Brizić, "Immune surveillance of cytomegalovirus in tissues", Cellular & Molecular Immunology, vol. 21, no. 9, pp. 959-981, August 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:088126. [Accessed: 05 October 2024]

Metadata
Title (english)Immune surveillance of cytomegalovirus in tissues
AuthorAndrea Mihalić
AuthorJelena Železnjak
AuthorBerislav Lisnić
AuthorStipan Jonjić
AuthorVanda Juranić Lisnić
AuthorIlija Brizić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Center for Proteomics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Cytomegalovirus (CMV), a representative member of the Betaherpesvirinae subfamily of herpesviruses, is common in the human population, but immunocompetent individuals are generally asymptomatic when infected with this virus. However, in immunocompromised individuals and immunologically immature fetuses and newborns, CMV can cause a wide range of often long-lasting morbidities and even death. CMV is not only widespread throughout the population but it is also widespread in its hosts, infecting and establishing latency in nearly all tissues and organs. Thus, understanding the pathogenesis of and immune responses to this virus is a prerequisite for developing effective prevention and treatment strategies. Multiple arms of the immune system are engaged to contain the infection, and general concepts of immune control of CMV are now reasonably well understood. Nonetheless, in recent years, tissue-specific immune responses have emerged as an essential factor for resolving CMV infection. As tissues differ in biology and function, so do immune responses to CMV and pathological processes during infection. This review discusses state-of-the-art knowledge of the immune response to CMV infection in tissues, with particular emphasis on several well studied and most commonly affected organs.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCellular & Molecular Immunology
Numberingvol. 21, no. 9, pp. 959-981
e-ISSN2042-0226
DOIhttps://doi.org/10.1038/s41423-024-01186-2
URN:NBNurn:nbn:hr:184:088126
Publication2024-08-12
ProjectNumber: KK.01.1.1.01.0006
Title (croatian): Jačanje kapaciteta CERVIRVAC-a za istraživanja u virusnoj imunologiji i vakcinologiji
Title (english): Strengthening the capacity of CerVirVac (Croatian Centre of Excellence for Virus Immunology and Vaccines) for research in viral immunology and vaccinology
Leader: Stipan Jonjić
Jurisdiction: eu
Funding stream: European Regional Development Fund
ProjectNumber: IP-2022-10-3371
Title (croatian): Latentna infekcija citomegalovirusom u središnjem živčanom sustavu
Title (english): Cytomegalovirus latency in the central nervous system
Acronym: CMV-CNS
Leader: Ilija Brizić
Jurisdiction: Croatia
Funding stream: Research Projects
ProjectNumber: IP-2020-02-3402
Title (croatian): Patogeneza citomegalovirusne infekcije u nadbubrežnoj žlijezdi
Title (english): Pathogenesis of the cytomegalovirus infection in the adrenal gland
Acronym: ADRENOPATH-CMV
Leader: Berislav Lisnić
Jurisdiction: Croatia
Funding stream: Research Projects
ProjectNumber: IP-2022-10-2324
Title (croatian): Karakterizacija prirođenog imunosnog odgovora na citomegalovirus u jajniku
Title (english): Characterizing innate immune responses to cytomegalovirus in the ovaries
Acronym: CIRCO
Leader: Vanda Juranić Lisnić
Jurisdiction: Croatia
Funding stream: Research Projects
Document URLhttps://www.nature.com/articles/s41423-024-01186-2
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-09-16 11:44:19