prikaz prve stranice dokumenta Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age
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Scientific paper - Chapter in Book
Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age
In: Polycystic Ovary Syndrome - Symptoms, Causes and Treatment / Wang, Zhengchao (Ed.). London: IntechOpen, 2024. pp. 1-12. https://doi.org/10.5772/intechopen.113150
Smiljan Severinski, Neda; Marton, Ulla; Radojčić Badovinac, Anđelka

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Smiljan Severinski, N., Marton, U. & Radojčić Badovinac, A. (2024). Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age. In Z. Wang, (Ed.), Polycystic Ovary Syndrome - Symptoms, Causes and Treatment (pp. 1-12). London: IntechOpen. doi: 10.5772/intechopen.113150

Smiljan Severinski, Neda, et al. "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age." Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, edited by Zhengchao Wang, IntechOpen, 2024, pp. 1-12. https://urn.nsk.hr/urn:nbn:hr:184:684603

Smiljan Severinski, Neda, Ulla Marton and Anđelka Radojčić Badovinac. "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age." In Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, edited by Zhengchao Wang, 1-12. London: IntechOpen, 2024. https://urn.nsk.hr/urn:nbn:hr:184:684603

Smiljan Severinski, N., Marton, U. and Radojčić Badovinac, A. (2024) 'Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age' in Wang, Z. (ed.) Polycystic Ovary Syndrome - Symptoms, Causes and Treatment London: IntechOpen, pp. 1-12. Available at: https://urn.nsk.hr/urn:nbn:hr:184:684603 (Accessed 01 January 2025)

Smiljan Severinski N, Marton U, Radojčić Badovinac A. Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age. In: Z. Wang, ed. Polycystic Ovary Syndrome - Symptoms, Causes and Treatment. London: IntechOpen; 2024. Pp. 1-12. [cited 2025 January 01] Available at: https://urn.nsk.hr/urn:nbn:hr:184:684603

N. Smiljan Severinski, U. Marton and A. Radojčić Badovinac, "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age", Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, Z. Wang, Ed. London: IntechOpen, 2024, pp. 1-12. [Online] Available at: https://urn.nsk.hr/urn:nbn:hr:184:684603

Metadata
Title (english)Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age
AuthorNeda Smiljan Severinski
AuthorUlla Marton
AuthorAnđelka Radojčić Badovinac
EditorZhengchao Wang
Author's institutionUniversity of Rijeka
(Faculty of Biotechnology and Drug Development)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Gynaecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
Polycystic ovary is part of an endocrine syndrome in which different pathophysiological mechanisms lead to a similar reproductive outcome: anovulation, irregularity of the menstrual cycle, and infertility. Hormonal and metabolic disorders are associated with reproductive adverse outcomes, which represent a vicious circle with dysfunctional ovaries. Hyperandrogenemia, disorder of carbohydrate metabolism, and sex hormone synthesis led to reproductive abnormalities. One of the most crucial questions still remains, whether the polycystic ovary is the cause or the consequence of all known disorders. Inositols are in the treatment of PCOS capable of restoring ovulation with the impact on the carbohydrate metabolism, by increasing the sensitivity of cells to insulin, which releases the sex hormones-binding protein and improves hyperandrogenemia. Nine stereoisomers of inositol are known, myo-inositol and chiro-inositol are the most studied in the reproductive age. By normalizing the level of androgens in the blood, the growth of and the balance of sex hormones is established. A variety of metabolic pathways of these molecules are recognized in different tissues, such as fat, muscle, or ovarian tissue. Still, it is not clear which isomer has better reproductive or metabolic effects, and there are controversies about their effectiveness in the treatment of reproductive disorders.
Keywords (english)
Languageenglish
Publication typeScientific paper - Chapter in Book
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Book titlePolycystic Ovary Syndrome - Symptoms, Causes and Treatment
Numberingpp. 1-12, 113150
ISBN978-0-85014-143-6
DOIhttps://doi.org/10.5772/intechopen.113150
URN:NBNurn:nbn:hr:184:684603
Publication2024-06-19
ProjectNumber: uniri-biomed-18-161
Title (croatian): Ekstracelularne vezikule humane folikularne tekućine: sadržaj i uloga u sazrijevanju oocite i kvaliteti embrija
Leader: Anđelka Radojčić-Badovinac
Jurisdiction: Croatia
Document URLhttps://www.intechopen.com/chapters/88333
Type of resourceText
PublisherIntechOpen
Publishing placeLondon
Access conditionsOpen access
Terms of useLicence Attribution 3.0 Unported (CC BY 3.0) icon
Created on2024-11-29 13:36:44