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Professional paper - Review paper
Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti
Medicina Fluminensis : Medicina Fluminensis, 47 (2011), 3; 269-274. urn:nbn:hr:184:465363
Brajac, Ines; Manestar, Teo; Malnar, Danijela

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Brajac, I., Manestar, T. & Malnar, D. (2011). Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti. Medicina Fluminensis : Medicina Fluminensis, 47. (3), 269-274. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:465363

Brajac, Ines, et al. "Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti." Medicina Fluminensis : Medicina Fluminensis, vol. 47, no. 3, 2011, pp. 269-274. https://urn.nsk.hr/urn:nbn:hr:184:465363

Brajac, Ines, Teo Manestar and Danijela Malnar. "Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti." Medicina Fluminensis : Medicina Fluminensis 47, no. 3 (2011): 269-274. https://urn.nsk.hr/urn:nbn:hr:184:465363

Brajac, I., Manestar, T. and Malnar, D. (2011) 'Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti', Medicina Fluminensis : Medicina Fluminensis, 47(3), pp. 269-274. Available at: https://urn.nsk.hr/urn:nbn:hr:184:465363 (Accessed 26 December 2024)

Brajac I, Manestar T, Malnar D. Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2011 September 05 [cited 2024 December 26];47(3):269-274. Available at: https://urn.nsk.hr/urn:nbn:hr:184:465363

I. Brajac, T. Manestar and D. Malnar, "Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti", Medicina Fluminensis : Medicina Fluminensis, vol. 47, no. 3, pp. 269-274, September 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:465363. [Accessed: 26 December 2024]

Metadata
Title (croatian)Neurobiologija kože: nove spoznaje i perspektive u liječenju kožnih bolesti
Title (english)Cutaneous neurobiology: modern concept and perspectives in the treatment of skin diseases
AuthorInes Brajac
AuthorTeo Manestar
AuthorDanijela Malnar
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract (croatian)
Koža je najgušće inerviran organ ljudskog tijela, u vrlo bliskom kontaktu sa živčanim sustavom. U međusobnu intenzivnu komunikaciju uključene su sve strukture živčanog, endokrinog i imunološkog sustava, kao i sve stanice kože. Interakcija je posredovana različitim tipovima kožnih živčanih vlakana koja otpuštaju neuromedijatore i aktiviraju specifične receptore na ciljnim stanicama kao što su keratinociti, mastociti, Langerhansove stanice, endotelne stanice, stanice mikrovaskulature, fibroblasti i infiltrirajuće imunološke stanice. Ove interakcije utječu na brojne fiziološke i patofiziološke funkcije, uključujući rast i razvoj stanica, diferencijaciju, imunost, vazoregulaciju i cijeljenje rana. Nova saznanja o čimbenicima uključenim u ove interakcije utvrdila su suvremeni koncept neurobiologije kože.
Abstract (english)
The skin is the most densely innervated organ in the body and there is a close relationship between the skin and the nervous system. Monodirectional and/or bidirectional pathways exist in which the central and peripheral nervous system, endocrine and immune system, and almost all skin cells are involved. The interaction between peripheral nerves and immune system is mediated by different types of cutaneous nerve fibers which release neuromediators and activate specific receptors on target cells in the skin such as keratinocytes, mast cells, Langerhans cells, microvascular endothelial cells, fibroblasts, and infiltrating immune cells. These interactions influence a variety of physiologic and pathophysiologic functions including cellular development, growth, differentiation, immunity, vasoregulation, leukocyte recruitment, pruritus, and wound healing. Information is emerging about the factors involved in these immunomodulatory mechanisms. Recent findings have established a modern concept of cutaneous neurobiology.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 47, no. 3, pp. 269-274
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:465363
Publication2011-09-05
Document URLhttp://hrcak.srce.hr/71754
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-05-10 10:03:36