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Scientific paper - Original scientific paper
Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis
Nutrients, 15 (2023), 15; 3335. https://doi.org/10.3390/nu15153335
Božić, Dorotea; Grgurević, Ivica; Mamić, Bisera; Čapkun, Vesna; Bilandžić-Ivišić, Josipa; Ivanović, Tomislav; Božić, Ivona; Žaja, Ivan; Podrug, Kristian; Puljiz, Željko; Perko, Zdravko; Mikolašević, Ivana

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Božić, D., Grgurević, I., Mamić, B., Čapkun, V., Bilandžić Ivišić, J., Ivanović, T. ... Mikolašević, I. (2023). Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis. Nutrients, 15. (15). doi: 10.3390/nu15153335

Božić, Dorotea, et al. "Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis." Nutrients, vol. 15, no. 15, 2023. https://doi.org/10.3390/nu15153335

Božić, Dorotea, Ivica Grgurević, Bisera Mamić, Vesna Čapkun, Josipa Bilandžić Ivišić, Tomislav Ivanović, Ivona Božić, et al. "Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis." Nutrients 15, no. 15 (2023). https://doi.org/10.3390/nu15153335

Božić, D., et al. (2023) 'Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis', Nutrients, 15(15). doi: 10.3390/nu15153335

Božić D, Grgurević I, Mamić B, Čapkun V, Bilandžić Ivišić J, Ivanović T, and sur.. Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis. Nutrients [Internet]. 2023 July 27 [cited 2024 October 03];15(15). doi: 10.3390/nu15153335

D. Božić, et al., "Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis", Nutrients, vol. 15, no. 15, July 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:937062. [Accessed: 03 October 2024]

Metadata
Title (english)Detection of Sarcopenia in Patients with Liver Cirrhosis Using the Bioelectrical Impedance Analysis
AuthorDorotea Božić
AuthorIvica Grgurević
AuthorBisera Mamić
AuthorVesna Čapkun
AuthorJosipa Bilandžić-Ivišić
AuthorTomislav Ivanović
AuthorIvona Božić
AuthorIvan Žaja
AuthorKristian Podrug
AuthorŽeljko Puljiz
AuthorZdravko Perko
AuthorIvana Mikolašević
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Bioelectrical impedance analysis (BIA) is a body composition assessment method. We aimed to determine its accuracy in the detection of sarcopenia in patients with liver cirrhosis (LC), using skeletal muscle index (SMI) at the level of third lumbar vertebra (L3-SMI) obtained using multislice computed tomography as the reference method. Patients with LC were enrolled in the period October 2019–March 2022 and follow-ups were conducted until January 2023. Their BIA parameters were compared against L3-SMI, and BIA cut-off values were proposed using AUROC analysis. Patients underwent outcome analysis based on obtained clinical characteristics. A total of 106 patients were included. We found a fair correlation between BIA parameters with the L3-SMI. We determined cut-off values of ≤11.1 kg/m2 for BIA-SMI (Se 73%, Sp 66%, AUROC 0.737, p < 0.001) and ≤5.05° for phase angle (PA) (Se 79%, Sp 60%, AUROC 0.762, p < 0.001) in the detection of sarcopenia. The relative risk of death was 2.2 times higher in patients with skeletal muscle mass (SMM) ≤ 36.5 kg. SMM was significantly associated with outcome in Kaplan–Meier analysis. This non-invasive and simple method that showed fair performances and a very good outcome prediction could provide for the unmet need for fast and affordable detection of sarcopenia in patients with LC and should be further evaluated.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleNutrients
Numberingvol. 15, no. 15, 3335
e-ISSN2072-6643
DOIhttps://doi.org/10.3390/nu15153335
URN:NBNurn:nbn:hr:105:937062
Publication2023-07-27
Document URLhttps://www.mdpi.com/2072-6643/15/15/3335
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-09-02 07:40:49