A singleton pregnancy is defined as the development of one fetus in the uterus, while a twin pregnancy is the development of two fetuses in the uterus. Planning nutrition and monitoring weight gain are crucial for maintaining the health of both the mother and fetus in any pregnancy. Guidelines and recommendations depend on the needs of singleton and twin pregnancies. The intake of the same nutrients is recommended, but in increased amounts for twin pregnancies. Antenatal care is an important part of every pregnancy. Non-invasive and invasive prenatal tests are essential for detecting chromosomal abnormalities and other complications. Ultrasound is used in singleton pregnancies to determine gestational age, early detection of anomalies, and monitoring fetal growth. In addition to these, in twin pregnancies, it is also used to differentiate zygosity and chorionicity. Singleton pregnancies usually last around 40 weeks, while twin pregnancies 37 weeks on average. Vaginal delivery is the safest option for both the fetus and the mother in term singleton pregnancies, making it the most common way to complete a singleton pregnancy. On the other hand, twins can be delivered vaginally in only about 40% of cases, with most being born via cesarean section. Twin pregnancies result in higher rates of preterm births and complications such as gestational diabetes and preeclampsia. There are universal guidelines for managing singleton pregnancies, whereas twin pregnancies often depend on the experience of the obstetrician due to a lack of specific guidelines. There is a higher incidence of maternal and perinatal complications in twin pregnancies compared to singleton pregnancies. In addition to fetal complications seen in singleton pregnancies, there are complications specific to monochorionic twins, such as twin-to-twin transfusion syndrome (TTTS) and twin anemia-polycythemia sequence (TAPS). Effective prenatal care and timely interventions are key to improving outcomes for both the mother and child in both types of pregnancies. Each pregnancy is unique and requires personalized considerations for favorable outcomes.