prikaz prve stranice dokumenta Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection
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Scientific paper - Original scientific paper
Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection
Blood Purification, 52 (2023), 7-8; 642-651. https://doi.org/10.1159/000531356
Premužić, Vedran; Šitum, Ivan; Lovrić, Daniel; Erceg, Ante; Karmelić, Dora; Moguš, Mate; Jurjević, Matija; Nedeljković, Vanja; Mažar, Mirabel; Mihaljević, Slobodan; Villa, Gianluca; Ronco, Claudio

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Premužić, V., Šitum, I., Lovrić, D., Erceg, A., Karmelić, D., Moguš, M. ... Ronco, C. (2023). Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection. Blood Purification, 52. (7-8), 642-651. doi: 10.1159/000531356

Premužić, Vedran, et al. "Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection." Blood Purification, vol. 52, no. 7-8, 2023, pp. 642-651. https://doi.org/10.1159/000531356

Premužić, Vedran, Ivan Šitum, Daniel Lovrić, Ante Erceg, Dora Karmelić, Mate Moguš, Matija Jurjević, et al. "Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection." Blood Purification 52, no. 7-8 (2023): 642-651. https://doi.org/10.1159/000531356

Premužić, V., et al. (2023) 'Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection', Blood Purification, 52(7-8), pp. 642-651. doi: 10.1159/000531356

Premužić V, Šitum I, Lovrić D, Erceg A, Karmelić D, Moguš M, and sur.. Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection. Blood Purification [Internet]. 2023 [cited 2025 January 03];52(7-8):642-651. doi: 10.1159/000531356

V. Premužić, et al., "Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection", Blood Purification, vol. 52, no. 7-8, pp. 642-651, 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:598473. [Accessed: 03 January 2025]

Metadata
Title (english)Sequential Extracorporeal Blood Purification Is Associated with Prolonged Survival among ICU Patients with COVID-19 and Confirmed Bacterial Superinfection
AuthorVedran Premužić
AuthorIvan Šitum
AuthorDaniel Lovrić
AuthorAnte Erceg
AuthorDora Karmelić
AuthorMate Moguš
AuthorMatija Jurjević
AuthorVanja Nedeljković
AuthorMirabel Mažar
AuthorSlobodan Mihaljević
AuthorGianluca Villa
AuthorClaudio Ronco
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Abstract (english)
Introduction: This study investigates the impact of sequential extracorporeal treatments with oXiris® or CytoSorb® plus Seraph-100® on the clinical and laboratory parameters of critically ill COVID-19 patients with bacterial superinfection. Methods: Patients admitted to the intensive care unit with COVID-19, bacterial superinfection, and undergoing blood purification (BP) were enrolled in this prospective, single-center, observational study. "standard BP" with oXiris® or CytoSorb® were used in 35 COVID-19 patients with bacterial infection. Seraph-100® was added in 33 patients when available serially in the same oXiris® circuit or as sequential treatment with CytoSorb® as a sequential BP. Results: A significant reduction in SOFA score 3 days after treatment was observed in patients undergoing sequential BP (11.3 vs. 8.17, p < 0.01) compared to those undergoing "standard BP" (11.0 vs. 10.3, p > 0.05). The difference between the observed and expected mortality rate based on APACHE IV was greater in the sequential BP group (42.4% vs. 81.7%, p < 0.001) than the "standard BP" (74.2% vs. 81.7%, p > 0.05). Patients treated with sequential BP had a longer survival than those treated with "standard BP" (22.4 vs. 18.7 months; p < 0.001). Conclusions: The sequential approach may enhance the positive effect of BP on organ dysfunction among critically ill patients with COVID-19 and bacterial superinfection.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBlood Purification
Numberingvol. 52, no. 7-8, pp. 642-651
p-ISSN0253-5068
e-ISSN1421-9735
DOIhttps://doi.org/10.1159/000531356
URN:NBNurn:nbn:hr:105:598473
Publication2023
Document URLhttps://karger.com/BPU/article/doi/10.1159/000531356
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-24 11:22:37