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master's thesis
Etiopatogeneza i liječenje svrbeža
Zagreb: University of Zagreb, School of Medicine, 2016. urn:nbn:hr:105:965815
Bubalo, Petra
University of Zagreb
School of Medicine
Department of Dermatology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Bubalo, P. (2016). Etiopatogeneza i liječenje svrbeža (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:965815

Bubalo, Petra. "Etiopatogeneza i liječenje svrbeža." Master's thesis, University of Zagreb, School of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:105:965815

Bubalo, Petra. "Etiopatogeneza i liječenje svrbeža." Master's thesis, University of Zagreb, School of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:105:965815

Bubalo, P. (2016). 'Etiopatogeneza i liječenje svrbeža', Master's thesis, University of Zagreb, School of Medicine, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:965815

Bubalo P. Etiopatogeneza i liječenje svrbeža [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2016 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:105:965815

P. Bubalo, "Etiopatogeneza i liječenje svrbeža", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:105:965815

Metadata
TitleEtiopatogeneza i liječenje svrbeža
Title (english)Etiopathogenesis and treatment of pruritus
AuthorPetra Bubalo
MentorSuzana Ljubojević Hadžavdić (mentor)
Committee memberZrinka Bukvić Mokos (predsjednik povjerenstva)
Committee memberKrešimir Kostović (član povjerenstva)
Committee memberSuzana Ljubojević Hadžavdić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Dermatology)
Zagreb
Defense date and country2016-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract
Kronični svrbež (KS) je vodeći simptom u mnogim dermatološkim i sistemskim bolestima i prisutan je u oko 8,4-22,6% opće populacije. Kronični svrbež, jednako kao i kronična bol, umanjuje kvalitetu života, ometa pacijenta u svakodnevnim aktivnostima i utječe na opće stanje pacijenta. Patofiziološki mehanizmi kroničnog svrbeža nisu još uvijek u potpunosti razjašnjeni. U oko 10-50% odraslih, svrbež može biti važan simptom mnogih sistemskih bolesti, poput bubrežne insuficijencije, kolestaze, hematoloških poremećaja, endokrinoloških ili malignih bolesti. Pacijentima s KS potreban je individualan pristup i liječenje koje odgovara stanju kože (praćeno upalom kože ili bez nje), mogućoj sistemskoj bolesti koja se nalazi u podlozi ovog simptoma te postojećoj primjeni lijekova. Terapija svrbeža može biti lokalna ili sistemska. Antihistaminici su prvi izbor kod KS, dok se fototerapija preporuča za generalizirani svrbež, antikonvulzivi te analgetici kod neuropatskog svrbeža, a antidepresivi kod KS koji je rezistentan na terapiju. Sistemski glukokortikosteroidi se ne preporučuju kao terapija svrbeža, osim u iznimnim i teškim oblicima.
Abstract (english)
Chronic pruritus (CP) is a major symptom in numerous dermatological and systemic diseases affecting 8,4-22,6% of population. CP can have a dramatic impact on the quality of life, similar to chronic pain, and it can worsen the general condition of the patient. The pathophysiological mechanisms are still insufficiently understood. In 10–50% of adults with persistent pruritus, it can be an important dermatologic clue for the presence of a significant underlying systemic disease such as renal insufficiency, cholestasis, hematologic disorder, endocrine disorder or malignancy. Patients with chronic pruritus require an individually therapy based on the condition of the skin (inflamed or non-inflamed), possible underlying causes and existing co-medication. Treatment for pruritus can be local or systemic. Antihistamines are fist-choice therapy in CP, while phototherapy is recommended for generalized pruritus, anticonvulsants and analgetics in neuropathic pruritus, and antidepressants in forms of CP not responding to other therapies. Systemic glucocorticosteroides are not recommended for treatment of CP except for severe cases.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:965815
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-06-28 11:36:41