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master's thesis
Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze
Zagreb: University of Zagreb, School of Medicine, 2016. urn:nbn:hr:105:424327
Legčević, Zoran
University of Zagreb
School of Medicine
Department of Medical Biology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Legčević, Z. (2016). Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:424327

Legčević, Zoran. "Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze." Master's thesis, University of Zagreb, School of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:105:424327

Legčević, Zoran. "Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze." Master's thesis, University of Zagreb, School of Medicine, 2016. https://urn.nsk.hr/urn:nbn:hr:105:424327

Legčević, Z. (2016). 'Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze', Master's thesis, University of Zagreb, School of Medicine, accessed 24 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:424327

Legčević Z. Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2016 [cited 2024 December 24] Available at: https://urn.nsk.hr/urn:nbn:hr:105:424327

Z. Legčević, "Povezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:105:424327

Metadata
TitlePovezanost polimorfizma osteoprotegrin gena s učestalošću aortalne stenoze
Title (english)Association of osteoprotegrin gene polymorphism with aortic stenosis
AuthorZoran Legčević
MentorFrane Paić (mentor)
Committee memberTamara Nikuševa Martić (predsjednik povjerenstva)
Committee memberLjiljana Šerman (član povjerenstva)
Committee memberFrane Paić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Medical Biology)
Zagreb
Defense date and country2016-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract
Brojna istraživanja pokazala su prisutnost različitih genetskih promjena kod pacijenata sa aortalnom stenozom. U ovom radu ispitan je utjecaj rs3102735 (C/T tranzicija, supstitucija) SNP polimorfizma OPG gena na učestalost aortalne stenoze. Ispitivana populacija (n= 223) obuhvaća 92 pacijenta sa dijagnosticiranom aortalnom stenozom i 131 zdrava dobrovoljca koji čine kontrolnu skupinu ispitanika. Nije uočena statistički značajna razlika u distribuciji genotipova i alela rs3102735 (C/T tranzicija, supstitucija) SNP polimorfizma OPG gena između AVS pacijenata i kontrolne skupine ispitanika.
Abstract (english)
Numerous research studies have shown association of genetic polimorphism with the prevalence of aortic valve stenosis. In this study we investigated the influence of rs3102735 (C/T transition, substitution) SNP polymorphism of OPG gene on incidence of aortic valve stenosis. Study population (n= 223) encompasses 92 aortic valve stenosis patients and 131 healthy control subjects. We did not detect any statistically significant difference in genotype or allele frequencies of rs3102735 between AVS patients and healthy control group.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:424327
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-10 07:32:10