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master's thesis
Funkcionalna kirurgija kod karcinoma grkljana
Zagreb: University of Zagreb, School of Medicine, 2017. urn:nbn:hr:105:011668
Šarac, Ivana
University of Zagreb
School of Medicine
Department of Othorhinolaryngology and Head and Neck Surgery

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Šarac, I. (2017). Funkcionalna kirurgija kod karcinoma grkljana (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:011668

Šarac, Ivana. "Funkcionalna kirurgija kod karcinoma grkljana." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:011668

Šarac, Ivana. "Funkcionalna kirurgija kod karcinoma grkljana." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:011668

Šarac, I. (2017). 'Funkcionalna kirurgija kod karcinoma grkljana', Master's thesis, University of Zagreb, School of Medicine, accessed 09 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:011668

Šarac I. Funkcionalna kirurgija kod karcinoma grkljana [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2017 [cited 2024 November 09] Available at: https://urn.nsk.hr/urn:nbn:hr:105:011668

I. Šarac, "Funkcionalna kirurgija kod karcinoma grkljana", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:105:011668

Metadata
TitleFunkcionalna kirurgija kod karcinoma grkljana
Title (english)Functional surgery of larynx carcinoma
AuthorIvana Šarac
MentorDrago Prgomet (mentor)
Committee memberMario Bilić (predsjednik povjerenstva)
Committee memberMirko Ivkić (član povjerenstva)
Committee memberDrago Prgomet (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Othorhinolaryngology and Head and Neck Surgery)
Zagreb
Defense date and country2017-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Otorhinolaryngology
Abstract
Tumori glave i vrata postaju sve učestaliji u Republici Hrvatskoj. Prema podacima iz 2013. godine, ovi tumori čine gotovo 7% novodijagnosticiranih zloćudnih tumora kod muškaraca te 1,5% kod žena. Mnogo je rizičnih faktora koji se povezuju s karcinomima glave i vrata: pušenje, kronična konzumacija alkohola, humani papiloma virus, izloženost radijaciji, prethodna povijest karcinoma glave i vrata itd. Više od 90% novodijagnosticiranih laringealnih karcinoma su karcinomi pločastih stanica, koji se mogu razviti u bilo kojem dijelu larinksa. Većina ih je smještena u glotičkom području; supraglotičko i subglotičko sijelo su nešto manje zastupljeni. Laringealni karcinom se može proširiti direktnim širenjem u okolne bliske strukture, putem metastaza u regionalne limfne čvorove ili na udaljena mjesta putem krvi. Ovisno o lokaciji, stadiju bolesti i tipu karcinoma, postoje različite metode liječenja. Liječenje ovih pacijenata je kompleksno zbog iznimno bitnih funkcija ove anatomske regije. Glavni cilj liječenja je ukloniti tumor i prevenirati rekurenciju, ako je moguće, uz očuvanje laringealnih funkcija. Terapija se mijenjala kroz nekoliko zadnjih desetljeća jer je do 1990-ih terapija izbora bila kirurgija. Parcijalna i totalna laringektomija su bile i još su uvijek glavna kirurška opcija, ali danas na raspolaganju imamo i kemoradioterapiju. Nova otkrića u endoskopskoj kirurgiji i laserskoj opremi predstavljaju budućnost u kirurškom liječenju karcinoma larinksa.
Abstract (english)
Incidence of head and neck cancer in Croatia is continuously increasing. According to data from 2013, these tumors make up almost 7% of newly diagnosed malignant tumors in men and 1,5% in women. There are many risk factors associated with head and neck cancer such as smoking, chronic consumption of alcohol, human papillomavirus, irradiation exposure, previous history of head and neck cancer etc. More than 90% newly diagnosed laryngeal cancers are squamous cell carcinoma, which can develop in any part of the larynx. Most of them originate in the glottis; supraglottic and subglottic sites are less common. Laryngeal carcinoma may spread by direct extension to the nearby structures, by metastasis to regional lymph nodes or more distantly through blood. Depending on the location, staging and type of the tumor there are different methods of treatment. Treatment of patients with laryngeal carcinoma is complex because of the crucial functions of this anatomic area. If possible, the goal is to remove the tumor and prevent reccurrence while maintaining laryngeal function. Treatment has changed over the past few decades because until the 1990s the only option was surgery. Partial and total laryngectomies were and still are the main surgical procedures to treat this carcinoma, but today chemoradiotherapy is also available. In addition, new developments in endoscopic surgery and laser equipment are the future in the treatment of the malignant laryngeal carcinoma.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:011668
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-01-11 11:06:51