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master's thesis
Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb
Zagreb: University of Zagreb, School of Medicine, 2017. urn:nbn:hr:105:162437
Brkić, Filip
University of Zagreb
School of Medicine
Department of Pediatrics

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Brkić, F. (2017). Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:162437

Brkić, Filip. "Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:162437

Brkić, Filip. "Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:162437

Brkić, F. (2017). 'Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb', Master's thesis, University of Zagreb, School of Medicine, accessed 25 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:162437

Brkić F. Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2017 [cited 2024 December 25] Available at: https://urn.nsk.hr/urn:nbn:hr:105:162437

F. Brkić, "Kratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:105:162437

Metadata
TitleKratkoročni ishod bolesnika s gastroshizom liječenih u Kliničkom bolničkom centru Zagreb
Title (english)Short term outcome in patients with gastroschisis treated in University Hospital Center Zagreb
AuthorFilip Brkić
MentorRuža Grizelj (mentor)
Committee memberJurica Vuković (predsjednik povjerenstva)
Committee memberMarija Jelušić (član povjerenstva)
Committee memberRuža Grizelj (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Pediatrics)
Zagreb
Defense date and country2017-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Intensive Care
Abstract
Gastroshiza je kongenitalna, najčešće izolirana malformacija prednje trbušne stijenke karakterizirana prolapsom abdominalnih organa, hipoplazijom trbušne šupljine i malrotacijom tankog i debelog crijeva. Takvo stanje nosi određene kratkoročne i dugoročne komplikacije. Cilj ovog retrospektivnog istraživanja, koje je obuhvatilo sve bolesnike liječene zbog gastroshize u Zavodu za neonatologiju i neonatalnu intenzivnu medicinu i Zavodu za gastroenterologiju, hepatologiju i prehranu Klinike za pedijatriju KBC-a Zagreb u periodu od svibnja 2007. godine do svibnja 2017. godine, bio je ispitati kratkoročne ishode u tih bolesnika. Iz medicinske dokumentacije izdvojili smo osnovne perinatalne i demografske podatke te kliničke karakteristike bolesnika. Potom, gastroshize smo podijelili, na temelju stanja gastrointestinalnog trakta kod poroda, na jednostavne i kompleksne te smo usporedili njihove karakteristike. Također, bilježili smo broj operacija i komplikacije tijekom hospitalizacije. Analizom podataka potvrdili smo dosadašnja stajališta: bolesnici s kompleksnim gastroshizama rađaju nezreliji (manje gestacijske dobi), rodna masa im je češće ispod 10.p. za gestaciju, imaju veći broj reoperacija i zahtijevaju značajno duže vrijeme za postizanje potpunog enteralnog unosa u odnosu na bolesnike s jednostavnim gastroshizama. Preživljenje naših bolesnika je u skladu s rezultatima drugih centara (>90%). Međutim, vrijeme do uspostave potpunog enteralnog unosa i vrijeme trajanja hospitalizacije je u našoj kohorti bolesnika značajno duže. Broj reoperacija i postojanje sepse su se izdvojili kao značajni čimbenici koji utječu na duljinu hospitalizacije. Naposljetku, većina bolesnika i nakon hospitalizacije zahtijeva dugoročan multidisciplinaran nadzor.
Abstract (english)
Gastroschisis is a congenital, usually isolated malformation of the anterior abdominal wall characterized by the prolapse of the abdominal organs, abdominal cavity hypoplasia and a malrotation of the small intestine and colon. Such condition bears certain short and long term complications. We conducted a retrospective cohort study of all gastroschisis cases treated between May 2007 and May 2017 in University Hospital Centre Zagreb, Department of pediatrics, Neonatal intensive care unit and Division of gastroenterology and hepatology. The aim of this study was to determine the short term outcomes of these patients. The medical records of 27 gastroschisis cases were reviewed for perinatal and demographic informations and clinical characteristics. Furthermore, we divided gastroschisis, based on the condition of gastrointestinal tract after birth, on simple and complex types and compared their characteristics. Also, we noted the number of surgical procedures and complications during the hospitalization. The analysis confirmed the current standpoint: patients with complex gastroschisis are born more immature (lower gestational age), their birthweight is more frequently under 10th percentile, they have higher number of resurgeries, and require significantly longer time to reach full enteral feeding compared to the patients with simple type. The survival rate is in accordance to the results of other centers (>90%). However, time to full enteral feeding and length of stay is significantly longer in our cohort. Also, number of resurgeries and presence of sepsis played significant roles in duration of hospitalization. Ultimately, most patients after hospitalization require a long term multidisciplinary supervision.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:162437
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-03-19 07:51:03