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master's thesis
Praćenje remisije kronične mijeloične leukemije nakon prekida terapije
Zagreb: University of Zagreb, School of Medicine, 2017. urn:nbn:hr:105:527097
Matić, Nikolina
University of Zagreb
School of Medicine
Department of Internal Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Matić, N. (2017). Praćenje remisije kronične mijeloične leukemije nakon prekida terapije (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:527097

Matić, Nikolina. "Praćenje remisije kronične mijeloične leukemije nakon prekida terapije." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:527097

Matić, Nikolina. "Praćenje remisije kronične mijeloične leukemije nakon prekida terapije." Master's thesis, University of Zagreb, School of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:105:527097

Matić, N. (2017). 'Praćenje remisije kronične mijeloične leukemije nakon prekida terapije', Master's thesis, University of Zagreb, School of Medicine, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:527097

Matić N. Praćenje remisije kronične mijeloične leukemije nakon prekida terapije [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2017 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:105:527097

N. Matić, "Praćenje remisije kronične mijeloične leukemije nakon prekida terapije", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:105:527097

Metadata
TitlePraćenje remisije kronične mijeloične leukemije nakon prekida terapije
Title (english)Chronic myeloid leukemia remission follow up after therapy discontinuation
AuthorNikolina Matić
MentorAna Boban (mentor)
Committee memberNadira Duraković (predsjednik povjerenstva)
Committee memberMarko Jakopović (član povjerenstva)
Committee memberAna Boban (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Zagreb
Defense date and country2017-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Kronična mijeloična leukemija (KML) specifična je zloćudna bolest s obzirom da je liječenje moguće provoditi peroralnim uzimanjem lijekova. Liječenje KML-a se bazira na dugogodišnjoj terapiji inhibitorima tirozin kinaze (TKI). Redovitom i pravilnom upotrebom ovog lijeka veliki broj bolesnika postiže remisiju bolesti, pri čemu je u uspjehu liječenja iznimno važan čimbenik suradljivost bolesnika u odnosu na redovitu primjenu lijeka i medicinske kontrole. Rutinska praksa podrazumijeva korištenje TKI i nakon što bolesnik postigne potpunu remisiju bolesti, no recentna znanstvena istraživanja navode uspjeh u održavanju zdravstvenog stanja i kontroli bolesti i nakon što se prekine terapija s TKI. Svrha ovoga rada je sustavnim pregledom literature prikupiti relevantne znanstvene činjenice o uspješnosti održavanja remisije KML nakon prekida terapije TKI.
Abstract (english)
Chronic myeloid leukaemia (CML) is a specific malignant disease as it can be managed by oral treatment. The patients with CML are treated by a long term tyrosine-kinase inhibitors (TKI). The remission of the disease can be achieved in majority of patients, and the tretment results depend largely on patient's compliance and regular taking of TKI. Current routine practise in themanagement of CML includes continuation of TKI therapy even after patient achieves deep remision. However, recent studies suggested that the disease can remain in remision even after the TKI discontinuation. The aim of this thesis is to asses of relevant scientific evidence on CML remission stability after TKI therapy cessation.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:527097
Study programmeTitle: Studies in Nursing
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-03-21 11:06:21