Although rare, tumors of the nose and paranasal sinuses are a big problem because of the late symptoms and proximity to important anatomical structures such as the eye and brain. After thoroughly made otorhynolaryngologycal examination, specialist indicates further investigation, imaging and biopsy. Treated primarily surgically, they can be treated with chemotherapy and radiotherapy or a combination of that two. In addition to the classical surgical procedures, endonasal endoscopic surgery is used, that kind of surgery is increasingly on the rise and its boundaries have not yet been reached. Over the past two decades, endoscopic endonasal surgery has become extremely popular and viable option for the treatment of lesions in this area. Our study shows that in the period of 2004-2012 in the Department of Otolaryngology and Head and Neck Surgery in University Hospital Sisters of Mercy a total of 1067 patients diagnosed with tumors of the nose and paranasal sinuses were operated. Of the total number of operations, most of them were excisions of skin tumors of nose (493), after excision in the number of procedures followes sinusoscopy. Overall, there is an increasing trend of surgical treatment, and endoscopic endonasal surgery is increasingly used both worldwide and in the Department of Otolaryngology and Head and Neck Surgery in University Hospital Sisters of Mercy.