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master's thesis
Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika
Zagreb: University of Zagreb, School of Medicine, 2018. urn:nbn:hr:105:674159
Matoković, Trpimir
University of Zagreb
School of Medicine
Department of Internal Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Matoković, T. (2018). Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:674159

Matoković, Trpimir. "Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika." Master's thesis, University of Zagreb, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:105:674159

Matoković, Trpimir. "Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika." Master's thesis, University of Zagreb, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:105:674159

Matoković, T. (2018). 'Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika', Master's thesis, University of Zagreb, School of Medicine, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:674159

Matoković T. Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2018 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:105:674159

T. Matoković, "Farmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:105:674159

Metadata
TitleFarmakoekonomska analiza terapijskih opcija za liječenje kaheksije u onkoloških bolesnika
Title (english)Pharmacoeconomic analysis of therapeutic options in cancer-induced cachexia
AuthorTrpimir Matoković
MentorRobert Likić (mentor)
Committee memberNadira Duraković (predsjednik povjerenstva)
Committee memberJasenka Markeljević (član povjerenstva)
Committee memberRobert Likić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Zagreb
Defense date and country2018-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Pharmacology and Toxicology
Abstract
Starenjem svjetske populacije incidencija malignih bolesti u stalnom je porastu. Kaheksija je jedan od najčešćih sindroma koji prate završne stadije malignih bolesti, a ne postoje unificirane službene smjernice za kliničko procjenjivanje ili terapiju kaheksije. U ovom preglednom radu biti će riječi o patofiziologiji i kliničkoj procjeni onkološke kaheksije, te o trenutno dostupnim terapijskim opcijama za liječenje iste. Cilj rada je usporediti učinkovitost različitih terapijskih opcija (stimulatori apetita, anabolički lijekovi, inhibitori citokina i imunomodulatori te ostale, uglavnom eksperimentalne, terapijske opcije) s njihovom cijenom i razinom dokaza kako bi predložio ekonomski povoljnu alternativu za potencijalna buduća istraživanja. ----- METODE: Pretražene su elektronske baze podataka PubMed i UpToDate.
Abstract (english)
World population is ageing and thus the incidence of malignant diseases is continuously rising. Cachexia is one of the most common syndromes occurring in the end stages of malignant diseases and there are no official guidelines for clinical assessment or therapy for it. This review will discuss pathophysiology, clinical assessment of cancer-induced cachexia and currently available therapeutic options. The focus of this review will be in comparing the effectiveness of available therapy (appetite stimulants, anabolic agents, cytokine and metabolic inhibitors and other, predominantly experimental, drugs) and strength of scientific evidence for the indication of cancer-cachexia with their costs to hopefully propose an economically favorable alternative for future research. ----- METHODS: electronic databases PubMed and UpToDate were searched.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:674159
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-01-18 10:20:17