prikaz prve stranice dokumenta Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.
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master's thesis
Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.
Zagreb: University of Zagreb, School of Medicine, 2018. urn:nbn:hr:105:324773
Hrnčić, Sandra
University of Zagreb
School of Medicine
Department of Infectious Diseases

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Hrnčić, S. (2018). Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017. (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:324773

Hrnčić, Sandra. "Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.." Master's thesis, University of Zagreb, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:105:324773

Hrnčić, Sandra. "Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.." Master's thesis, University of Zagreb, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:105:324773

Hrnčić, S. (2018). 'Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.', Master's thesis, University of Zagreb, School of Medicine, accessed 05 January 2025, https://urn.nsk.hr/urn:nbn:hr:105:324773

Hrnčić S. Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017. [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2018 [cited 2025 January 05] Available at: https://urn.nsk.hr/urn:nbn:hr:105:324773

S. Hrnčić, "Loss to follow-up in HIV infected persons in Croatia in period 2006.-2017.", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:105:324773

Metadata
TitleLoss to follow-up in HIV infected persons in Croatia in period 2006.-2017.
Title (croatian)Gubitak osoba zaraženih HIV-om iz praćenja u Republici Hrvatskoj u razdoblju od 2006. do 2017. godine
AuthorSandra Hrnčić
MentorJosip Begovac (mentor)
Committee memberDavorka Lukas (predsjednik povjerenstva)
Committee memberGoran Tešović (član povjerenstva)
Committee memberJosip Begovac (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Zagreb
Defense date and country2018-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract
In Croatia healthcare is public and antiretroviral therapy (ART) is covered by health insurance. The following study investigates the possible risk factors influencing rates of LTFU. Database of patients followed in the University hospital for infectious disease (UHIC) Zagreb, the centre holding data for all HIV infected persons followed in the period between 1.7.2006. and 1.7.2016. in Croatia was used. We extracted the data from the electronic database at UHID and included into study all Croatian residents ≥ 18 years old, with at least one year of follow-up and at least 2 visits. LTFU was defined as present if there was no visit for 12 months or the patient had no ART supplies for more than 3 months. The follow-up ended on december 31, 2017 or earlier if the patient died, moved or interrupted care. Associations between factors and LTFU rates were quantified using repeated measures Poisson regression. Of 1091 patients, 240 (22%) had a total of 336 episodes of LTFU. The rate of LTFU was 4.23 (95% CI, 3.80–4.70) per 100 person-years. Multivariable predictors of UHCI included viral load (VL) >200 copies/ml (Incidence Rate Ratio (IRR)) 1.77 (95% CI:1.42–2.20), age (per 10 years) IRR 0.84 (95% CI: 0.76–0.93), prior UHCI (per episode) IRR 3.49 (95% CI: 3.04–4.00), calendar year (2006–2009 vs 2010–2016) IRR 1.50 (95% CI 1.20–1.87) and time under follow-up (per year) IRR 1.14 (95% CI 1.11–1.18). Of 240 patients with at least one UHCI 16 (6.7%) died whereas of 851 without an LTFU 44 (5.2%) died (P=0.369). Measured < 200 cell/mm 3 had no definite correlation with LTFU rates when comparing bivariate and multivariate analysis . At the last visit at UHID, of 240 patients with an LTFU 127 (52.9%) had reentered care, 16 had died, 8 moved and 89 (37.1%) had an LTFU.
Abstract (croatian)
U Hrvatskoj zdravstvena zaštita je javna i antiretroviralna terapija (ART) je pokrivena zdravstvenim osiguranjem. Ovo istraživanje preispituje moguće faktore rizika koji utiću na stope gubitka iz praćenja (GIP). Korištena je baza podataka pacijenata praćenih Sveućilišnoj bolnici za infektivne bolesti klinike u Zagrebu, centra koji sadrži podatke svih osoba zaraženih HIV-om praćenih u Hrvatskoj u periodu između 1.7.2006. I 1.7.2016.Izvadili smo podatke iz elektronske baze podataka klinike za infektivne bolesti i uključili u istraživanje sve stanovnike Republike Hrvatske koji imaju ≥ 18 godina, sa barem godinu dana praćenja i barem 2 posjeta. Gubitak iz njege je definiran kao postojeći kada nema niti jednog posjeta klinici 12 mjeseci ili pacijent nije imao ART zalihe za više od 3 mjeseca. Praćenje je završilo 31. Prosinca, 2017. ili ranije ako je pacijent umro, preselio se ili prekinuo sa njegom. Poveznice između faktora i stopa GIP su kvantificirane koristeći Poissonovu regresiju ponovljenih mjerenja.Od 1091 pacijenata , 240 (22%) je iskusilo ukupno 336 episode GIP. Stopa GIP je bila 4.23 (95% CI, 3.80–4.70) po 100 osoba-godina. Multivarijatni predkazivači GIP uključivali su koncentraciju virusa >200 kopija/ml (Incidence Rate Ratio (IRR)) 1.77 (95% CI:1.42–2.20), dob (per 10 years) IRR 0.84 (95% CI: 0.76–0.93), prijašnje GIC (po epizodi) IRR 3.49 (95% CI: 3.04–4.00), kalendarske godine (2006–2009 vs 2010–2016) IRR 1.50 (95% CI 1.20–1.87) i vrijeme praćenja (po godini) IRR 1.14 (95% CI 1.11–1.18). Od 240 pacijenata sa barem jednim GIP 16 (6.7%) je umrlo dok od 851 bez GIP 44 (5.2%) je umrlo (P=0.369). Izmjereni CD4 < 200 cell/mm 3 nisu imali korelaciju sa stopama GIP kada su bivarijatna i multivarijantna analiza uspoređene. Pri zadnjem posjetu bolnici, od 240 osoba sa GIP, 127 (52.9%) je ponovno ušlo u praćenje, 16 je umrlo, 8 se odselilo i 89 (37.1%) je imalo GIP.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:324773
Study programmeTitle: Medicine (in English language)
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-04-23 11:30:59