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master's thesis
Klinički spektar frontotemporalne lobarne degeneracije
Zagreb: University of Zagreb, School of Medicine, 2014. urn:nbn:hr:105:189239
Paić, Marina
University of Zagreb
School of Medicine
Department of Neurology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Paić, M. (2014). Klinički spektar frontotemporalne lobarne degeneracije (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:189239

Paić, Marina. "Klinički spektar frontotemporalne lobarne degeneracije." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:189239

Paić, Marina. "Klinički spektar frontotemporalne lobarne degeneracije." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:189239

Paić, M. (2014). 'Klinički spektar frontotemporalne lobarne degeneracije', Master's thesis, University of Zagreb, School of Medicine, accessed 25 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:189239

Paić M. Klinički spektar frontotemporalne lobarne degeneracije [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2014 [cited 2024 April 25] Available at: https://urn.nsk.hr/urn:nbn:hr:105:189239

M. Paić, "Klinički spektar frontotemporalne lobarne degeneracije", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:105:189239

Metadata
TitleKlinički spektar frontotemporalne lobarne degeneracije
Title (english)Clinical spectrum of frontotemporal lobar degeneration
AuthorMarina Paić
MentorMarina Boban (mentor)
Committee memberBranko Malojčić (predsjednik povjerenstva)
Committee memberMario Habek (član povjerenstva)
Committee memberMarina Boban (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Neurology)
Zagreb
Defense date and country2014-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract
Frontotemporalna lobarna degeneracija (FTLD) je u dobi do 65. godine života druga najučestalija vrsta demencije uz Alzheimerovu bolest. Od Alzheimerove bolesti se razlikuje po tome što amnestički sindrom nije dominantan u ranijim stadijima bolesti. Klinički se očituje progresivnim poremećajima ponašanja i govora uzrokovanih degeneracijom u frontalnim i prednjim dijelovima temporalnih režnjeva. U oko polovine oboljelih nalazi se nasljedna podloga, što se povezuje najčešće s mutacijom MAPT gena. FTLD obuhvaća spektar klinički, patološki i genetski raznolikih neurodegenerativnih poremećaja. U zavisnosti od anatomske raspodjele patoloških promjena može se razlikovati više kliničkih sindroma: bihevioralna (frontalna) varijanta FTLD-a, progresivna nefluentna afazija, semantička demencija i dr.
Abstract (english)
Frontotemporal lobar degeneration (FTLD) is the second most common type of dementia under the age of 65, first being Alzheimer's disease. In contrast to Alzheimer's disease, amnestic syndrome is not characteristic early feature of FTLD. It's clinically characterised by a progressive decline in behaviour and language caused by degeneration of frontal and anterior temporal lobes. In about half of patients there is a hereditary basis, which is primarily associated with mutations in MAPT gene. FTLD includes a range of clinical, pathological and genetic variety of neurodegenerative disorders. Depending on the anatomical distribution of pathological lesions, multiple clinical syndromes can be distinguished: behavioural (frontal) variant frontotemporal lobar degeneration, progressive non-fluent aphasia, semantic dementia and others.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:189239
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2015-10-28 12:17:51