In this paper, the psychopathology of schizophrenia is presented and explained in detail; groups of mental disorders that have the common existence of various cognitive, emotional and behavioral dysfunctions. With related disorders of personality, schizophrenia belongs to F20 by ICD-10 classification. This disease, whose causes and pathogenesis despite the great effort and numerous studies that are still unknown, affects all people regardless of the place or time of their being. The prognosis of the disease depends on several factors, and modern treatment has allowed the life of an individual outside the institution. There are exactly defined conditions for the diagnosis of schizophrenia (by ICD-10 classification), and the ultimate purpose of treating is reintegration into society. It is the symptomatology of schizophrenia, the disease that most often begins in adolescence, that is an extremely wide area. A variety of clinical image and varying severity of illness, condition a unique picture of schizophrenia in each affected individual. In some, in the early stages of the disease, clear, visible, sudden and serious symptoms will be marked; while in others, diseases will begin slowly, gradually, without clearly visible symptoms. A thoroughly elaborated clinical picture and symptoms that are divided into positive, negative, cognitive, social, and bodily signs and symptoms are the main part of the work. Detailed explanations clearly point to the relationship with the impact on the overall impression and presentation of the patient. Also, there are elaborated phases of the disease characterized by the associated symptomatic symptoms and the division of schizophrenia.