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master's thesis
Uloga liječnika obiteljske medicine u dijagnostici celijakije
Zagreb: University of Zagreb, School of Medicine, 2019. urn:nbn:hr:105:059823
Market, Marija
University of Zagreb
School of Medicine
Department of Internal Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Market, M. (2019). Uloga liječnika obiteljske medicine u dijagnostici celijakije (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:059823

Market, Marija. "Uloga liječnika obiteljske medicine u dijagnostici celijakije." Master's thesis, University of Zagreb, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:105:059823

Market, Marija. "Uloga liječnika obiteljske medicine u dijagnostici celijakije." Master's thesis, University of Zagreb, School of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:105:059823

Market, M. (2019). 'Uloga liječnika obiteljske medicine u dijagnostici celijakije', Master's thesis, University of Zagreb, School of Medicine, accessed 09 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:059823

Market M. Uloga liječnika obiteljske medicine u dijagnostici celijakije [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2019 [cited 2024 November 09] Available at: https://urn.nsk.hr/urn:nbn:hr:105:059823

M. Market, "Uloga liječnika obiteljske medicine u dijagnostici celijakije", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:105:059823

Metadata
TitleUloga liječnika obiteljske medicine u dijagnostici celijakije
Title (english)The role of family doctor in diagnosis of celiac disease
AuthorMarija Market
MentorSilvija Čuković-Čavka (mentor)
Committee memberĐurđica Kašuba Lazić (predsjednik povjerenstva)
Committee memberJasenka Markeljević (član povjerenstva)
Committee memberSilvija Čuković-Čavka (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Zagreb
Defense date and country2019-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Family Medicine
Abstract
Celijakija (CD) je sustavna, imunološki posredovana bolest, koju izaziva gluten iz pšenice i srodni prolamini koji se nalaze u ječmu i raži. Pojavljuje se u 1% opće populacije. Simptomatologija je izrazito varijabilna i ovisna o dobi. Kod djece je češća klasična klinička slika koja se prezentira između sedmog i dvadest i četvrtog mjeseca života. Kod odraslih postoje dvije skupine simptoma, crijevni i vancrijevni. Mnogi pacijenti imaju blage simptome bez znakova malapsorpcije ili ih uopće nemaju. Dijagnostika kod odraslih je bazirana na serološkom testiranju i dokazu atrofije na patohistološkoj analizi sluznice dvanaesnika. Preporuča se testirati i asimptomatske osobe s povišenim rizikom za razvoj celijakije.. Dijagnostika djece obavlja se u nekim slučajevima bez biopsije crijeva ako osoba ima klasičnu kliničku sliku, visok titar protutijela u dva različita uzorka krvi te dokazane promjene DQ2DQ8 heterodimera. Obiteljski liječnik ima ključnu ulogu u prepoznavanju i dijagnostici celijakije, praćenju pacijenata i probiru osoba s povišenim rizikom za razvoj celijakije.
Abstract (english)
Celiac disease is a systemic, immune-mediated disease caused by gluten from wheat and related prolamins found in barley and rye. Appears in 1% of the general population. Symptomatology is highly variable and age-dependent. Children are more likely to develop classical clinical manifestations which are presented between the seventh and twenty fourth months of life. In adults, there are two groups of symptoms, intestinal and extraintestinal. Many patients have mild symptoms without signs of malabsorption or have no symptoms at all. Adult diagnosis is based on serological testing and histopathological analysis of the duodenal mucosa which proves atrophy. Testing is recommended to asymptomatic people at high risk of developing celiac disease. Diagnosis of children can be done without duodenal biopsy if a person has a classical symptoms, a high antibody levels in two different blood samples and alter DQ2DQ8 heterodimers proven. A family doctor plays a key role in recognizing and diagnosing celiac disease, monitoring patients, and screening people at high risk of developing celiac disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:059823
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-02-13 10:10:32