The family is the fundamental social group based on common life inner circle of blood relatives and members who are not necessarily in blood relation, and it unites the biological – reproductive, educational and economic functions. Although it should be a safe place of every individual, there are families in which there are conflicts and disagreements that manifest the various forms of violence. There are several types of violence, which are divided into physical violence, psychological violence, sexual harassment, economic violence and neglect. The ultimate form of domestic violence ends fatal consequences and in this case we are talking about a intrafamily homicide. Homicide is an unlawful, violent, deliberate and intent ional act of taking a person's life. Considering the relation among victim and perpetrator, types of intrafamily homicide include infanticide, paricide (patricid / matridicid), siblicide (fratricide / sororicide), maricide and uxoricide. This paper analyzes intrafamily homicide victims autopsied at The Department of Forensic Medicine at the Faculty of Medicine of the University of Zagreb from 1998. to 2017. The study included 97 victim and 90 perpetrators. The characteristics of the victim and perpetrator, their relationship, the choice of weapon and the frequency of suicide of the perpetrator depending on the relationship with the victim are analyzed. Victims were more often women, and perpetrators were mainly men. Considering the relation among victim and perpetrator, victim was mostly marital or extramarital spouse. Firearms was most used for committing the offense of homicide. A quarter of the total number of perpetrators committed suicide after committing a homicide.