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Scientific paper - Original scientific paper
The use of infrared technology as a novel approach for studies with female laboratory animals
Croatian Medical Journal, 61 (2020), 4; 346-363. https://doi.org/10.3325/cmj.2020.61.346
Ratko, Martina; Habek, Nikola; Kordić, Milan; Dugandžić, Aleksandra

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Ratko, M., Habek, N., Kordić, M. & Dugandžić, A. (2020). The use of infrared technology as a novel approach for studies with female laboratory animals. Croatian Medical Journal, 61. (4), 346-363. doi: 10.3325/cmj.2020.61.346

Ratko, Martina, et al. "The use of infrared technology as a novel approach for studies with female laboratory animals." Croatian Medical Journal, vol. 61, no. 4, 2020, pp. 346-363. https://doi.org/10.3325/cmj.2020.61.346

Ratko, Martina, Nikola Habek, Milan Kordić and Aleksandra Dugandžić. "The use of infrared technology as a novel approach for studies with female laboratory animals." Croatian Medical Journal 61, no. 4 (2020): 346-363. https://doi.org/10.3325/cmj.2020.61.346

Ratko, M., et al. (2020) 'The use of infrared technology as a novel approach for studies with female laboratory animals', Croatian Medical Journal, 61(4), pp. 346-363. doi: 10.3325/cmj.2020.61.346

Ratko M, Habek N, Kordić M, Dugandžić A. The use of infrared technology as a novel approach for studies with female laboratory animals. Croatian Medical Journal [Internet]. 2020 August 31 [cited 2024 December 24];61(4):346-363. doi: 10.3325/cmj.2020.61.346

M. Ratko, N. Habek, M. Kordić and A. Dugandžić, "The use of infrared technology as a novel approach for studies with female laboratory animals", Croatian Medical Journal, vol. 61, no. 4, pp. 346-363, August 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:314489. [Accessed: 24 December 2024]

Metadata
Title (english)The use of infrared technology as a novel approach for studies with female laboratory animals
AuthorMartina Ratko
AuthorNikola Habek
AuthorMilan Kordić
AuthorAleksandra Dugandžić
Author's institutionUniversity of Zagreb
School of Medicine
(Croatian Institiute for Brain Research)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Physiology and Immunology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Physiology
Abstract (english)
Aim To determine the changes in skin temperature and brown adipose tissue (BAT) activity throughout the estrous cycle as well as the regularity of the estrous cycle in mice. ----- Methods We assessed the differences in the duration of the estrous cycle and its phases between 3- and 8-month-old female mice (n = 18). Skin temperature and BAT activity were measured by infrared technology and compared with human menstrual cycle. ----- Results Young and old female mice did not differ significantly in the estrous cycle length. However, young animals had longer diestrus and shorter proestrus phase. In contrast with women, mice showed age-dependent changes in body temperature and BAT activity during the estrus cycle. ----- Conclusion Establishing the pattern of temperature and BAT activity changes could be used to determine the estrous cycle phase before performing experiments without disturbing the animal. However, since the regulation of BAT activity during the estrous cycle was age-dependent, very complex, and varied significantly from women, further studies are needed to develop a non-invasive method for determining the phase of the estrous cycle.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 61, no. 4, pp. 346-363
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2020.61.346
URN:NBNurn:nbn:hr:105:314489
Publication2020-08-31
Document URLhttp://www.cmj.hr/2020/61/4/32881433.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2020-10-29 12:26:34