prikaz prve stranice dokumenta Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart
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Scientific paper - Review paper
Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart
Croatian Medical Journal, 61 (2020), 2; 126-138. https://doi.org/10.3325/cmj.2020.61.126
Svaguša, Tomo; Martinić, Mislav; Martinić, Matea; Kovačević, Lucija; Šepac, Ana; Miličić, Davor; Bulum, Joško; Starčević, Boris; Sirotković-Skerlev, Maja; Seiwerth, Fran; Kulić, Ana; Sedlić, Filip

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Svaguša, T., Martinić, M., Martinić, M., Kovačević, L., Šepac, A., Miličić, D. ... Sedlić, F. (2020). Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart. Croatian Medical Journal, 61. (2), 126-138. doi: 10.3325/cmj.2020.61.126

Svaguša, Tomo, et al. "Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart." Croatian Medical Journal, vol. 61, no. 2, 2020, pp. 126-138. https://doi.org/10.3325/cmj.2020.61.126

Svaguša, Tomo, Mislav Martinić, Matea Martinić, Lucija Kovačević, Ana Šepac, Davor Miličić, Joško Bulum, et al. "Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart." Croatian Medical Journal 61, no. 2 (2020): 126-138. https://doi.org/10.3325/cmj.2020.61.126

Svaguša, T., et al. (2020) 'Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart', Croatian Medical Journal, 61(2), pp. 126-138. doi: 10.3325/cmj.2020.61.126

Svaguša T, Martinić M, Martinić M, Kovačević L, Šepac A, Miličić D, and sur.. Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart. Croatian Medical Journal [Internet]. 2020 April 30 [cited 2024 May 03];61(2):126-138. doi: 10.3325/cmj.2020.61.126

T. Svaguša, et al., "Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart", Croatian Medical Journal, vol. 61, no. 2, pp. 126-138, April 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:828961. [Accessed: 03 May 2024]

Metadata
Title (english)Mitochondrial unfolded protein response, mitophagy and other mitochondrial quality control mechanisms in heart disease and aged heart
AuthorTomo Svaguša
AuthorMislav Martinić
AuthorMatea Martinić
AuthorLucija Kovačević
AuthorAna Šepac
AuthorDavor Miličić
AuthorJoško Bulum
AuthorBoris Starčević
AuthorMaja Sirotković-Skerlev
AuthorFran Seiwerth
AuthorAna Kulić
AuthorFilip Sedlić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Pathology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract (english)
Mitochondria are involved in crucial homeostatic processes in the cell: the production of adenosine triphosphate and reactive oxygen species, and the release of pro-apoptotic molecules. Thus, cell survival depends on the maintenance of proper mitochondrial function by mitochondrial quality control. The most important mitochondrial quality control mechanisms are mitochondrial unfolded protein response, mitophagy, biogenesis, and fusion-fission dynamics. This review deals with mitochondrial quality control in heart diseases, especially myocardial infarction and heart failure. Some previous studies have demonstrated that the activation of mitochondrial quality control mechanisms may be beneficial for the heart, while others have shown that it may lead to heart damage. Our aim was to describe the mechanisms by which mitochondrial quality control contributes to heart protection or damage and to provide evidence that may resolve the seemingly contradictory results from the previous studies.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 61, no. 2, pp. 126-138
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2020.61.126
URN:NBNurn:nbn:hr:105:828961
Publication2020-04-30
Document URLhttp://www.cmj.hr/2020/61/2/32378379.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2020-11-05 17:02:41