Title (croatian) Glavobolja uzrokovana prekomjernom upotrebom lijekova Title (english) Medication-overuse headache Author Zlatko Hucika Author Damir Petravić Author's institution University of Zagreb Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract (croatian) Glavobolja uzrokovana prekomjernom upotrebom lijekova (GUPUL) definira se kao sekundarna glavobolja
u bolesnika s prethodnom primarnom glavoboljom, najčešće migrenom ili tenzijskom glavoboljom, koja se
javlja u prosjeku 15 i više dana mjesečno kao posljedica redovite prekomjerne primjene akutne simptomatske
terapije za glavobolju (10 i više ili 15 i više dana mjesečno, ovisno o lijeku koji se upotrebljava) tijekom više od
3 mjeseca. Temeljem radova nađenih pretraživanjem baze podataka PubMed u zadnjih 15 godina raspravljamo
o definiciji, epidemiologiji, patofiziologiji, kliničkoj slici, dijagnostici, terapiji, prognozi i prevenciji GUPUL-a.
Cilj ovog preglednog rada jest probuditi svijest među liječnicima da je GUPUL česta dijagnoza u bolesnika s
primarnim glavoboljama koju treba adekvatno tretirati, a čiji je razvoj moguće prevenirati već na razini primarne
zdravstvene zaštite.
Abstract (english) Medication-overuse headache (MOH) is defined as a secondary headache in patients with previous
primary headache, mostly migraine or tension headache, present for 15 or more days per month due to the
overuse of acute symptomatic therapy for headache (10 or more or 15 or more days per month, depending on the
medication used) and persisting for more than 3 months. Based on the papers published in the past 15 years on
the topic, identified by searching the PubMed database, definition, epidemiology, pathophysiology,clinical
picture,
diagnosis, therapy, prognosis and prevention of MOH are discussed. The aim of this review is to make
physicians aware of the fact that MOH is a frequent diagnosis among patients with primary headaches, which
needs to be treated appropriately but the development of which can be prevented at the primary healthcare level.
Keywords (croatian)
SEKUNDARNA GLAVOBOLJA – dijagnoza, kemijski izazvana, liječenje, patofiziologija, prevencija
ANALGETICI – neželjeni učinci, terapijska uporaba
TENZIJSKE GLAVOBOLJE – farmakoterapija
MIGRENA – farmakoterapija
KOMORBIDITET
PROGNOZA
Keywords (english)
HEADACHE DISORDERS, SECONDARY – chemically induced, diagnosis, physiopathology, prevention and control
ANALGESICS – adverse effects, therapeutic use
TENSION-TYPE HEADACHE – drug therapy
MIGRAINE DISORDERS – drug therapy
COMORBIDITY
PROGNOSIS
Language croatian Publication type Scientific paper - Review paper Publication status Published Peer review Peer review Publication version Published version Journal title Liječnički vjesnik Numbering vol. 142, no. 7-8, pp. 230-238 p-ISSN 0024-3477 e-ISSN 1849-2177 DOI https://doi.org/10.26800/LV-142-7-8-38 URN:NBN urn:nbn:hr:105:337068 Publication 2020 Document URL https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=353584 Type of resource Text Access conditions Open access Terms of use Created on 2020-11-26 10:11:46
